| Type | Description |
|---|---|
| Definition | crystallin alpha A |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:13:00 | Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of alpha-crystallin: Implications for lens aging and presbyopia. | 32184356 |
| 2020-02-29 11:09:00 | Human crystallin alpha A contains two cysteines, which can form an intramolecular disulfide in vivo. Oxidation in vitro requires conformational changes and oligomer dissociation. The oxidized oligomers, which are larger than reduced crystallin alpha A and destabilized against unfolding. | 31792453 |
| 2019-12-14 11:57:00 | Structural and functional consequences of age-related isomerization in alpha-crystallins. | 30804217 |
| 2019-12-07 10:49:00 | Study demonstrated the neuroprotective role of alphaA-crystallin during diabetes and its regulation by its phosphorylation on residue 148 and further characterized the dual role of alphaA-crystallin in neurons and glia, its essential role for neuronal survival, and its direct dependence on phosphorylation on this residue. | 29467334 |
| 2019-05-25 10:04:00 | A novel mutation in the CRYAA gene is associated with congenital cataract and microphthalmia in a Chinese family. | 30340470 |
| Type | IDs |
|---|---|
| Synonymous | CRYA1, CTRCT9, HSPB4 |
| Gene |
UniProtKB-ID:
CRYA2_HUMAN,
CRYAA_HUMAN
UniprotKB:
A0A140G945,
P02489
UniParc:
UPI0000128380,
UPI0000206C2B
EMBL:
KM220588,
X14789,
FP236240,
M35629,
BC113598,
KM220589,
KM220592,
CH471079,
M35628,
AP001748,
U66584,
KM220590,
KM220591,
AP001631,
BC069528,
CR407691,
U05569
Ensembl:
ENSG00000276076,
ENSG00000160202
KO:
hsa:1409,
hsa:102724652
|
| Nucleutide sequences |
EMBL-CDS:
AMM63586.1,
AMM63585.1,
AMM63587.1,
AMM63583.1,
AMM63584.1,
AAA97523.1,
AAH69528.1,
EAX09497.1,
AAC50900.1,
CAG28619.1,
AAA52105.1,
EAX09498.1,
AAA52106.1,
AAI13599.1,
BAA95535.1,
CAA32891.1
Ensembl_TRS:
ENST00000624932,
ENST00000619537,
ENST00000291554
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482816,
ENSP00000485302,
ENSP00000291554
RefSeq:
NP_000385.1,
NP_001350695.1
|
| Others |
UniRef100:
UniRef100_A0A140G945
UniRef90:
UniRef90_A0A140G945
UniRef50:
UniRef50_P24622
UniGene:
Hs.184085
CCDS:
CCDS82651.1,
CCDS82652.1,
CCDS13695.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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