| Type | Description |
|---|---|
| Definition | splicing regulatory glutamic acid and lysine rich protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism. | 32533168 |
| 2011-01-29 10:58:00 | From among the 500 splicing events exhibiting altered splicing under these conditions, the splicing of c-Jun and IkappaBbeta were validated as being regulated by SRrp86 resulting in altered regulation of their downstream targets. | 20400856 |
| 2010-01-21 00:00:00 | the unique glutamic acid-lysine domain of SRrp86 plays a modulatory role controlling serine-arginine domain function | 12183448 |
| 2010-01-21 00:00:00 | SRrp86 can activate SRp20 and repress SC35 in a dose-dependent manner both in vitro and in vivo | 11991645 |
| 2010-01-21 00:00:00 | p18SRP is a lysine-rich zinc finger domain-containing protein that interacts with the serine-arginine-rich splicing regulatory protein SRrp86; it is downregulated in brain of Alzheimer disease patients. | 15456940 |
| Type | IDs |
|---|---|
| Synonymous | SFRS12, SRrp508, SRrp86 |
| Gene |
UniProtKB-ID:
SREK1_HUMAN
UniprotKB:
Q8WXA9
UniParc:
UPI00000467F2,
UPI000007375A
EMBL:
AF459094,
BC047322,
BC067770,
BC112343
Ensembl:
ENSG00000153914
KO:
hsa:140890
|
| Nucleutide sequences |
EMBL-CDS:
AAL67778.1,
AAH47322.1,
AAH67770.1,
AAI12344.1
Ensembl_TRS:
ENST00000380918,
ENST00000334121
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370305,
ENSP00000334538
RefSeq:
XP_016864545.1,
NP_001070667.1,
NP_001310462.1,
NP_001310463.1,
NP_001310458.1,
NP_001257421.1,
NP_631907.1,
NP_001310464.1,
XP_016864544.1,
XP_011541473.1,
NP_001310456.1
|
| Others |
UniRef100:
UniRef100_Q8WXA9
UniRef90:
UniRef90_Q8WXA9
UniRef50:
UniRef50_Q8WXA9
UniGene:
Hs.49367
CCDS:
CCDS43323.1,
CCDS3991.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员