| Type | Description |
|---|---|
| Definition | Fanconi anemia, complementation group C |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 11:39:00 | FancA(-/-) and FancC(-/-) embryos have abnormal skeletal development shown by skeletal malformations, growth delay, and reduced bone mineralization. | 29989666 |
| 2019-02-23 11:38:00 | TP53 haploinsufficiency completely rescues emergency granulopoiesis in FANCC(-/-) mice. | 29427417 |
| 2017-01-14 11:57:00 | Genetic deletion of Fancc blocks the autophagic clearance of viruses (virophagy) and increases susceptibility to lethal viral encephalitis. Fanconi anemia complementation group C (FANCC) protein interacts with Parkin, is required in vitro and in vivo for clearance of damaged mitochondria, and decreases mitochondrial reactive oxygen species production and inflammasome activation. | 27133164 |
| 2016-09-10 12:06:00 | Data show that Fanconi anemia, complementation group C protein knockout (Fancc -/-) mice develop hematopoietic chromosomal instability followed by leukemia in an age-dependent manner. | 26860989 |
| 2016-08-06 10:33:00 | Loss of Fancc Impairs Antibody-Secreting in Mice through Deregulating the Wnt Signaling Pathway | 26895835 |
| Type | IDs |
|---|---|
| Synonymous | Facc |
| Gene |
UniProtKB-ID:
FANCC_MOUSE,
Q8CBR3_MOUSE,
E9QAE8_MOUSE,
Q3UI88_MOUSE
UniprotKB:
P50652,
Q8CBR3,
E9QAE8,
Q3UI88
UniParc:
UPI000164C528,
UPI0000021C00,
UPI00005AC5E4,
UPI00000E9481
EMBL:
CT009757,
AK147025,
AC130827,
AK035488,
AC154638,
L08266
Ensembl:
ENSMUSG00000021461
KO:
mmu:14088
|
| Nucleutide sequences |
EMBL-CDS:
AAA37590.1,
BAC29076.1,
BAE27618.1
Ensembl_TRS:
ENSMUST00000163091,
ENSMUST00000073029,
ENSMUST00000161977,
ENSMUST00000099444
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124406,
ENSMUSP00000123817,
ENSMUSP00000072788,
ENSMUSP00000097043
RefSeq:
XP_011242787.1,
NP_001334444.1,
XP_036013738.1,
XP_036013739.1,
XP_006517153.1,
XP_030103005.1,
NP_032011.2,
XP_030103004.1,
XP_036013741.1,
XP_011242784.1,
XP_011242785.1,
XP_011242786.1,
XP_030103008.1,
XP_011242777.1,
XP_011242778.1,
XP_011242779.1,
NP_001334443.1,
XP_011242776.1,
NP_001036138.1,
XP_011242783.1,
XP_011242780.1,
XP_036013737.1,
XP_011242782.1,
NP_001269871.1,
XP_006517150.1,
XP_036013740.1,
XP_030103007.1,
XP_017170871.1
|
| Others |
UniRef100:
UniRef100_P50652,
UniRef100_Q8CBR3
UniRef90:
UniRef90_P50652
UniRef50:
UniRef50_Q00597
UniGene:
Mm.126106
CCDS:
CCDS84029.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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