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140862 ISM1

140862

ISM1

isthmin 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition isthmin 1

研究结论

Date Results Publications
2021-04-17 13:14:00 Regulation of N-glycosylation and secretion of Isthmin-1 by its C-mannosylation. 33412225
2020-05-16 12:23:00 we identify ISM1 as an extracellular antagonist of NODAL and reveal a negative regulatory mechanism that provides greater plasticity for the fine-tuning of NODAL signaling. 31171630
2020-05-16 10:32:00 MiR-1307-3p inhibited activation of Wnt3a/beta-catenin signaling through targeting downregulation of ISM1. 31513891
2018-10-06 10:19:00 Our study demonstrates a successful pipeline from CNV identification of a candidate gene to functional validation in a vertebrate model system, and reveals Isthmin 1 as both a new human clefting locus as well as a key craniofacial patterning gene. 29162626
2015-06-20 10:46:00 Given that ISM1 has been reported to have anti-angiogenic properties, these observations suggest that ISM1 is a mediator of lymphocyte effector functions and may participate in both innate and acquired immune responses. 24956034

名称对应

Type IDs
Synonymous C20orf82, ISM, Isthmin, bA149I18.1, dJ1077I2.1
Gene
UniProtKB-ID: ISM1_HUMAN
UniprotKB: B1AKI9
UniParc: UPI00004A0D4C
EMBL: AL050320, CH471133, AL133463, BC017997
Ensembl: ENSG00000101230
KO: hsa:140862
Nucleutide sequences
EMBL-CDS: AAH17997.1, EAX10318.1
Ensembl_TRS: ENST00000262487
Protein sequencees
Ensembl_PRO: ENSP00000262487
RefSeq: XP_016883169.1, NP_543016.1
Others
UniRef100: UniRef100_B1AKI9
UniRef90: UniRef90_B1AKI9
UniRef50: UniRef50_B1AKI9
UniGene: Hs.559353
CCDS: CCDS46579.1

全选

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研究热度

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