Fadd - Fas (TNFRSF6)-associated via death domain-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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14082 Fadd

基因描述

Type	Description
Definition	Fas (TNFRSF6)-associated via death domain

研究结论

Date	Results	Publications
2021-03-13 13:16:00	OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.	32075762
2020-11-21 13:15:00	Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration.	31239234
2020-06-20 10:39:00	The promotion of PSCs activation in knocking down SPOP with siSPOP-1 were counteracted by knocking down FADD.	31493386
2020-05-30 13:23:00	Sevoflurane attenuated FRET efficiency, indicating that sevoflurane hindered the interaction between Fas DD and FADD. The predicted sevoflurane binding site is known to play a significant role in Fas DD-FADD interaction, supporting our in vitro and in vivo apoptosis results.	31513427
2019-10-05 10:38:00	this study demonstrates that FADD is a critical regulator of the intestinal intraepithelial lymphocytes development	30250469

名称对应

Type	IDs
Synonymous	Mort1/FADD
Gene	UniProtKB-ID: FADD_MOUSE UniprotKB: Q61160 UniParc: UPI0000001868 EMBL: U50406, BC004584, AK169798, BC021400, AK084808, AK170927, U43184 Ensembl: ENSMUSG00000031077 KO: mmu:14082
Nucleutide sequences	EMBL-CDS: BAC39283.1, AAA97876.1, AAB07789.1, AAH04584.1, AAH21400.1, BAE42120.1, BAE41374.1 Ensembl_TRS: ENSMUST00000033394
Protein sequencees	Ensembl_PRO: ENSMUSP00000033394 RefSeq: NP_034305.1
Others	UniRef100: UniRef100_Q61160 UniRef90: UniRef90_Q61160 UniRef50: UniRef50_Q13158 UniGene: Mm.5126 CCDS: CCDS22050.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
33271062	RIPK1 Promotes Energy Sensing by the mTORC1 Pathway. Mol Cell Ayaz Najafov , Hoang Son Luu , Adnan K Mookhtiar , Lauren Mifflin , Hong-Guang Xia , Palak P Amin , Alban Ordureau , Huibing Wang , Junying Yuan	2021-01-21	-
31869420	Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease. J Exp Med R K Subbarao Malireddi , Prajwal Gurung , Sannula Kesavardhana , Parimal Samir , Amanda Burton , Harisankeerth Mummareddy , Peter Vogel , Stephane Pelletier , Sandeepta Burgula , Thirumala-Devi Kanneganti	2020-03-02	-
32075762	OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis. Cell Rep Lien Verboom , Arne Martens , Dario Priem , Esther Hoste , Mozes Sze , Hanna Vikkula , Lisette Van Hove , Sofie Voet , Jana Roels , Jonathan Maelfait , Laura Bongiovanni , Alain de Bruin , Charlotte L Scott , Yvan Saeys , Manolis Pasparakis , Mathieu J M Bertrand , Geert van Loo	2020-02-18	-
30988397	RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ Santosh Krishna-Subramanian , Stephan Singer , Marietta Armaka , Jesus M Banales , Kerstin Holzer , Peter Schirmacher , Henning Walczak , George Kollias , Manolis Pasparakis , Vangelis Kondylis	2019-12-01	-
31723262	Activity of caspase-8 determines plasticity between cell death pathways. Nature Kim Newton , Katherine E Wickliffe , Allie Maltzman , Debra L Dugger , Rohit Reja , Yue Zhang , Merone Roose-Girma , Zora Modrusan , Meredith S Sagolla , Joshua D Webster , Vishva M Dixit	2019-11-01	-
31513427	The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction. FASEB J. Sophia Koutsogiannaki , Lifei Hou , Hasan Babazada , Toshiaki Okuno , Nathan Blazon-Brown , Sulpicio G Soriano , Takehiko Yokomizo , Koichi Yuki	2019-11-01	-
31493386	SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis. Exp. Cell Res. Peng Tan , Ankang Wang , Hao Chen , Yichao Du , Baolin Qian , Hao Shi , Yajun Zhang , Xianming Xia , Wenguang Fu	2019-11-01	-
31519886	Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis. Nat Commun Xixi Zhang , Haiwei Zhang , Chengxian Xu , Xiaoming Li , Ming Li , Xiaoxia Wu , Wenjuan Pu , Bin Zhou , Haikun Wang , Dali Li , Qiurong Ding , Hao Ying , Hui Wang , Haibing Zhang	2019-09-13	-
31519887	K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation. Nat Commun Yong Tang , Hailin Tu , Jie Zhang , Xueqiang Zhao , Yini Wang , Jun Qin , Xin Lin	2019-09-13	-
31239234	Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration. J Diabetes Complications Sarah I Lindstrom , Sigrun Sigurdardottir , Thomas E Zapadka , Jie Tang , Haitao Liu , Brooklyn E Taylor , Dawn G Smith , Chieh A Lee , John DeAngelis , Timothy S Kern , Patricia R Taylor	2019-09-01	-

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