| Type | Description |
|---|---|
| Definition | acyl-CoA synthetase long-chain family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:39:00 | Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia. | 32146873 |
| 2020-05-30 12:03:00 | loss of ACSL1 in macrophages decreases fatty acid crystal formation thereby reducing lysosome damage and IL-1beta release. | 31166619 |
| 2020-02-22 10:37:00 | ACSL1 deficiency produces an overall defect in muscle fuel metabolism that increases protein catabolism, resulting in exercise intolerance, muscle weakness, and myocyte apoptosis. | 30975900 |
| 2019-11-02 11:04:00 | Short-term cardiac-specific ACSL1 inactivation resulted in metabolic and transcriptional derangements distinct from those observed upon complete ACSL1 knockout, suggesting heart-specific mTOR (mechanistic target of rapamycin) signaling that occurs during the early stages of substrate switching. | 29622588 |
| 2017-06-03 12:11:00 | ACSL1-mediated metabolic trapping of exogenous LCFA accelerates LCFA uptake rates, albeit to a lesser extent in females, which distinctly affects LCFA trafficking to acyl intermediates but not triglyceride storage or mitochondrial oxidation and is affected by female sex hormones. | 26995156 |
| Type | IDs |
|---|---|
| Synonymous | Acas, Acas1, Acs, FACS, Facl2, LACS 1, LACS1 |
| Gene |
UniProtKB-ID:
ACSL1_MOUSE
UniprotKB:
P41216
UniParc:
UPI000016927D
EMBL:
AK161189,
BC056644,
AK004897,
AK145900,
AK149406,
U15977,
AK168078,
AK153050,
AK152772
Ensembl:
ENSMUSG00000018796
KO:
mmu:14081
|
| Nucleutide sequences |
EMBL-CDS:
BAE31484.1,
BAE26736.1,
BAE40051.1,
BAE36230.1,
AAH56644.1,
AAA52193.1,
BAE28854.1,
BAE31678.1,
BAB23652.1
Ensembl_TRS:
ENSMUST00000034046,
ENSMUST00000110372
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034046,
ENSMUSP00000106001
RefSeq:
XP_006509325.2,
XP_030099145.1,
XP_006509327.1,
NP_001289092.1,
XP_036009645.1,
XP_006509329.1,
XP_017168052.1,
XP_006509328.1,
NP_032007.2
|
| Others |
UniRef100:
UniRef100_P41216
UniRef90:
UniRef90_P18163
UniRef50:
UniRef50_P18163
UniGene:
Mm.210323
CCDS:
CCDS22291.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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