| Type | Description |
|---|---|
| Definition | sulfiredoxin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:29:00 | Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer. | 32411320 |
| 2020-02-22 10:40:00 | Sulfiredoxin exhibits an increased association with TXNDC5, facilitating the retention of Srx in the endoplasmic reticulum. The cellular levels of Srx and TXNDC5 may be useful as biomarkers to predict the survival of individuals with lung cancer. | 31000628 |
| 2019-06-22 10:10:00 | Srx expression, MDA levels, and levels in BGC823 cells were markedly inhibited upon treatment with diallyl trisulfide (DATS), a major constituent of garlic oil with proven anticancer effects. These results suggest that Srx may be an oxidative stress marker. Antioxidation may account for the anticancer potential of garlic. | 30863778 |
| 2018-12-01 10:25:00 | NRF2, DJ1 and SRNX1 are commonly expressed in diffusely infiltrating astrocytomas and they can be used in predicting patient prognosis. | 29441509 |
| 2018-03-31 11:55:00 | Study identify a role for Srxn1 as a denitrosylase for neuronal Prx2. Finding points to the NO/Srxn1 pair in a previously unrecognized redox cycle that modulates Prx2 peroxidase activity. | 27821734 |
| Type | IDs |
|---|---|
| Synonymous | C20orf139, Npn3, SRX, SRX1 |
| Gene |
UniProtKB-ID:
SRXN1_HUMAN
UniprotKB:
Q9BYN0
UniParc:
UPI000000DC3B
EMBL:
BC032604,
AK312054,
BC047707,
AL833944,
AL121758,
BC017001
Ensembl:
ENSG00000271303
KO:
hsa:140809
|
| Nucleutide sequences |
EMBL-CDS:
AAH47707.1,
AAH32604.1,
CAD38799.1,
BAG34990.1,
AAH17001.1
Ensembl_TRS:
ENST00000381962
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000371388
RefSeq:
NP_542763.1
|
| Others |
UniRef100:
UniRef100_Q9BYN0
UniRef90:
UniRef90_Q9BYN0
UniRef50:
UniRef50_Q9BYN0
UniGene:
Hs.516830
CCDS:
CCDS13005.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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