| Type | Description |
|---|---|
| Definition | SMCR8-C9orf72 complex subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:09:00 | Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. | 32848248 |
| 2020-08-01 12:06:00 | Our study not only illustrates the basis of C9ORF72-SMCR8-WDR41 complex assembly but also reveals the GAP activity of the C9ORF72-SMCR8 complex | 32303654 |
| 2017-11-18 12:16:00 | While focusing on the role of SMCR8 during autophagy initiation, we found that kinase activity and gene expression of ULK1 are increased upon SMCR8 depletion. The latter phenotype involved association of SMCR8 with the ULK1 gene locus. | 28195531 |
| 2017-10-28 13:20:00 | Study describes the identification of two binding partners for C9orf72: SMCR8 and WDR41 and demonstrated that C9orf72/SMCR8/WDR41 interacts with the FIP200/Ulk1/ATG13/ATG101 complex. | 27193190 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SMCR8_HUMAN
UniprotKB:
Q8TEV9
UniParc:
UPI000006DC1E,
UPI0000E0322D
EMBL:
BC101117,
BC014179,
BC001018,
BC142680,
AF467440,
BC101116
Ensembl:
ENSG00000283741,
ENSG00000176994
KO:
hsa:140775
|
| Nucleutide sequences |
EMBL-CDS:
AAI01117.1,
AAH01018.1,
AAL78337.1,
AAI01118.1,
AAH14179.1,
AAI42681.1
Ensembl_TRS:
ENST00000406438,
ENST00000639332
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000492062,
ENSP00000385025
RefSeq:
NP_658988.2
|
| Others |
UniRef100:
UniRef100_Q8TEV9
UniRef90:
UniRef90_Q8TEV9
UniRef50:
UniRef50_Q8TEV9
UniGene:
Hs.592944,
Hs.707728
CCDS:
CCDS11195.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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