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14071 F9

14071

F9

coagulation factor IX

protein-coding

Mus musculus

基因描述

Type Description
Definition coagulation factor IX

研究结论

Date Results Publications
2019-01-12 10:18:00 Protein S is an important in vivo inhibitor of FIXa. Disruption of the interaction between PS and FIXa causes an increased rate of thrombus formation in mice. 29419409
2018-06-09 11:24:00 Authors investigated the interaction of coagulation factor IX in the development of atherosclerosis. Severe deficiency of FIX did not protect the animals from the development of atherosclerotic plaques in the aortic areas. 28709017
2017-07-01 12:31:00 activation peptide of factor IX regulates endothelial intercellular adhesion and thus could be used in the treatment of vascular hyperpermeability. 27392935
2013-07-13 11:28:00 structural features within residues of the 39-loop contribute to the resistance of FIXa to inhibition by plasma inhibitors ZPI and TFPI. 23530052
2013-02-09 10:31:00 Data indicate that the hyperactivating factor IX (FIX)-R338L mutation resulted in a robust 15-fold gain in potency and therefore provides a promising strategy to improve the efficacy, feasibility, and safety of hemophilia gene therapy. 23043073

名称对应

Type IDs
Synonymous AW111646, Cf-9, Cf9
Gene
UniProtKB-ID: FA9_MOUSE
UniprotKB: P16294
UniParc: UPI00001E4073
EMBL: M26236, AK149372, M23109
Ensembl: ENSMUSG00000031138
KO: mmu:14071
Nucleutide sequences
EMBL-CDS: AAA37629.1, BAE28840.1, AAA37630.1
Ensembl_TRS: ENSMUST00000033477
Protein sequencees
Ensembl_PRO: ENSMUSP00000033477
RefSeq: NP_032005.1, NP_001292726.1, XP_030107081.1
Others
UniRef100: UniRef100_P16294
UniRef90: UniRef90_P16294
UniRef50: UniRef50_P00740
UniGene: Mm.391283
CCDS: CCDS30158.1

全选

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研究热度

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