| Type | Description |
|---|---|
| Definition | coagulation factor VIII |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:36:00 | A Foundational Study for Normal F8-Containing Mouse Models for the miRNA Regulation of Hemophilia A: Identification and Analysis of Mouse miRNAs that Downregulate the Murine F8 Gene. | 32781510 |
| 2020-11-21 13:12:00 | Hemophilia A and B mice, but not VWF(-/-)mice, display bone defects in congenital development and remodeling after injury. | 31594977 |
| 2020-10-24 13:56:00 | TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding. | 31465300 |
| 2019-02-23 13:07:00 | The increased immunogenicity of oxidized FVIII was not reverted by treatment of mice with N-acetyl cysteine, and did not implicate an increased maturation of professional antigen-presenting cells. Data document that oxidation influences the immunogenicity of therapeutic FVIII. | 29395036 |
| 2018-12-01 10:21:00 | Haemophilic animals (F8(-/-) mice) fed a high fat/fructose diet are highly prone to hepatic steatosis and thrombocytopenia. | 29656466 |
| Type | IDs |
|---|---|
| Synonymous | Cf-8, Cf8, FVIII |
| Gene |
UniProtKB-ID:
FA8_MOUSE,
B2RRC9_MOUSE,
B7ZNH8_MOUSE,
Q8BQ43_MOUSE
UniprotKB:
Q06194,
B2RRC9,
B7ZNH8,
Q8BQ43
UniParc:
UPI0001747A5F,
UPI0000193225,
UPI000189A929,
UPI00000EAFCC
EMBL:
AK051579,
AL808110,
CH466576,
AL731844,
BC138347,
BC145245,
L05573
Ensembl:
ENSMUSG00000031196
KO:
mmu:14069
|
| Nucleutide sequences |
EMBL-CDS:
EDL29229.1,
AAA37385.1,
AAI38348.1,
AAI45246.1,
BAC34681.1
Ensembl_TRS:
ENSMUST00000033539,
ENSMUST00000114085
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033539,
ENSMUSP00000109719
RefSeq:
NP_032003.2,
NP_001154845.1,
NP_001154846.1,
XP_006527853.1,
XP_006527854.1,
XP_006527852.1,
XP_006527855.1
|
| Others |
UniRef100:
UniRef100_B7ZNH8,
UniRef100_B2RRC9,
UniRef100_Q06194
UniRef90:
UniRef90_Q06194
UniRef50:
UniRef50_Q06194
UniGene:
Mm.1805
CCDS:
CCDS30238.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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