Flt3 - fms-related tyrosine kinase 3-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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140635 Flt3

基因描述

Type	Description
Definition	fms-related tyrosine kinase 3

研究结论

Date	Results	Publications
2012-01-14 11:13:00	synergizes with granulocyte-colony-stimulating factor in bone marrow stem cell mobilization	21539498
2010-01-21 00:00:00	This novel cross-talk between GR and a hematopoietic growth factor might also imply glucocorticoid effects on Flt3-mediated signaling.	18261979
2010-01-21 00:00:00	The FLT3 receptor is activated at the late stages of liver regeneration and participates in the proliferation response that is observed during progenitor-dependent liver regeneration.	18031378

名称对应

Type	IDs
Gene
Nucleutide sequences
Protein sequencees	RefSeq: NP_001094292.1
Others	UniGene: Rn.6774

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
24184354	NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease. Exp. Hematol. Rachel Rau , Daniel Magoon , Sarah Greenblatt , Li Li , Colleen Annesley , Amy S Duffield , David Huso , Emily McIntyre , John G Clohessy , Markus Reschke , Pier Paolo Pandolfi , Donald Small , Patrick Brown	2014-02-01	Flt3, Npm1, Flt3, Npm1
23969938	Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia. Clin. Cancer Res. Sharyn D Baker , Eric I Zimmerman , Yong-Dong Wang , Shelley Orwick , Douglas S Zatechka , Jassada Buaboonnam , Geoffrey A Neale , Scott R Olsen , Eric J Enemark , Sheila Shurtleff , Jeffrey E Rubnitz , Charles G Mullighan , Hiroto Inaba	2013-10-15	Flt3
23528453	The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity. Exp. Cell Res. Karin Gustafsson , Garrett Heffner , Pamela L Wenzel , Matthew Curran , Jan GrawÃ© , Shannon L McKinney-Freeman , George Q Daley , Michael Welsh	2013-07-15	-
23418353	The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor. J. Cell. Sci. Christopher J Smith , Donna M Berry , C Jane McGlade	2013-03-15	Flt3, Rnf115, Rnf126, SCAMP3, CCDC50, EGFR, RNF115, RNF126, UBE2D2, UBE2N, CBL
22674806	Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias. Blood Nicholas A Zorko , Kelsie M Bernot , Susan P Whitman , Ronald F Siebenaler , Elshafa H Ahmed , Gabriele G Marcucci , Daniel A Yanes , Kathleen K McConnell , Charlene Mao , Chidimma Kalu , Xiaoli Zhang , David Jarjoura , Adrienne M Dorrance , Nyla A Heerema , Benjamin H Lee , Gang Huang , Guido Marcucci , Michael A Caligiuri	2012-08-02	-
22187040	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML. Br J Cancer W-H Lin , W-T Jiaang , C-W Chen , K-J Yen , S-Y Hsieh , S-C Yen , C-P Chen , K-Y Chang , C-Y Chang , T-Y Chang , Y-L Huang , T-K Yeh , Y-S Chao , C-T Chen , J T-A Hsu	2012-01-31	-
21539498	Flt3 ligand synergizes with granulocyte-colony-stimulating factor in bone marrow mobilization to improve functional outcome after spinal cord injury in the rat. Cytotherapy Lucia UrdzikovÃ¡ , KatarÃna LikavÄanovÃ¡-MaÅ¡ÃnovÃ¡ , VÃ¡clav VanÄÄek , JiÅÃ RÅ¯Å¾iÄka , JiÅÃ SedÃ½ , Eva SykovÃ¡ , Pavla JendelovÃ¡	2011-10-01	-
21813452	Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation. Blood Shabnam Kharazi , Adam J Mead , Anna Mansour , Anne Hultquist , Charlotta BÃ¶iers , Sidinh Luc , Natalija Buza-Vidas , Zhi Ma , Helen Ferry , Debbie Atkinson , Kristian Reckzeh , Kristina Masson , JÃ¶rg Cammenga , Lars RÃ¶nnstrand , Fumio Arai , Toshio Suda , Claus Nerlov , Ewa Sitnicka , Sten Eirik W Jacobsen	2011-09-29	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21487043	FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis. Cancer Res. Christophe Desterke , Chrystele Bilhou-NabÃ©ra , Bernadette Guerton , Christophe Martinaud , Carole Tonetti , Denis Clay , Paola Guglielmelli , Alessandro Vannucchi , Dominique Bordessoule , Hans Hasselbalch , Brigitte Dupriez , Nassima Benzoubir , Marie-FranÃ§oise Bourgeade , Olivier Pierre-Louis , Vladimir Lazar , William Vainchenker , Annelise Bennaceur-Griscelli , Heinz Gisslinger , StÃ©phane Giraudier , Marie-Caroline Le Bousse-KerdilÃ¨s , French Intergroup of Myeloproliferative Disorders, , French INSERM , European EUMNET Networks on Myelofibrosis	2011-04-15	Flt3lg, Flt3, FLT3

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