| Type | Description |
|---|---|
| Definition | transcription factor AP-2 alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:27:00 | Kctd15 regulates nephron segment development by repressing Tfap2a activity. | 33028614 |
| 2020-07-04 10:43:00 | Insights into the genetic control of differentiation, where tfap2a is essential for regulating a suite of segment transporter traits at the final tier of zebrafish pronephros ontogeny. These findings have relevance for understanding renal birth defects, as well as efforts to recapitulate nephrogenesis in vivo to facilitate drug discovery and regenerative therapies. | 31160420 |
| 2019-11-09 12:19:00 | We genetically ablate the NC using double mutants of tfap2a;tfap2c or remove specific subsets of the NC with sox10 and mitfa knockouts and characterise genome-wide gene expression levels across multiple time points. | 31199790 |
| 2017-06-24 10:54:00 | Genetic interaction between tfap2a and mitfa suggest that the factors encoded by these genes regulate shared targets in melanocytes, possibly within single or converging pathways. | 28249010 |
| 2015-12-26 11:17:00 | these data support a model in which Tfap2a, acting through Bmp7a, modulates Fgf and Notch signaling to control the duration, amount and speed of SAG neural development. | 25781991 |
| Type | IDs |
|---|---|
| Synonymous | ap2, ap2a, cb93, fb83f04, fc31a07, wu:fb83f04, wu:fc31a07 |
| Gene |
UniProtKB-ID:
A0A2R8QRQ5_DANRE,
Q6NYI3_DANRE,
F1QUT4_DANRE
UniprotKB:
A0A2R8QRQ5,
Q6NYI3,
F1QUT4
UniParc:
UPI00076093F1,
UPI0000D8BE3C,
UPI000035878B
EMBL:
BC066582,
LO018137,
LO018134
Ensembl:
ENSDARG00000059279
KO:
dre:140618
|
| Nucleutide sequences |
EMBL-CDS:
AAH66582.1
Ensembl_TRS:
ENSDART00000186660,
ENSDART00000183624,
ENSDART00000082351
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000157668,
ENSDARP00000148170,
ENSDARP00000076787
RefSeq:
NP_789829.2,
NP_001306088.1,
NP_001306087.1,
XP_005162615.1
|
| Others |
UniRef100:
UniRef100_F1QUT4,
UniRef100_A0A2R8QRQ5,
UniRef100_A0A2R8RSI4
UniRef90:
UniRef90_F1QUT4
UniRef50:
UniRef50_F1QUT4
UniGene:
Dr.8506
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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