| Type | Description |
|---|---|
| Definition | coagulation factor II |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:42:00 | Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin. | 32000579 |
| 2020-08-01 15:02:00 | Data show that bone marrow kinase on the X chromosome (BMX) specifically repressed thrombin-PAR1 (protease-activated receptor-1) signaling in endothelial cells by directly phosphorylating PAR1 and promoting its internalization and deactivation. | 31910739 |
| 2019-11-02 11:22:00 | Thrombin induced VEGF release from astrocytes require p44/42. Thrombin induced VEGF release from astrocytes is reduced in PAR-1 knockout mice. Thrombin induced p44/42 activation in astrocytes is blocked in PAR-1 knockout mice. | 30606478 |
| 2018-11-10 11:21:00 | These results suggested that the thrombinstimulated synthesis of IL6 was limited by HSP90 in osteoblasts, and that the effects of HSP90 were exerted at the point between Rhokinase and p38 MAPK. | 30066835 |
| 2017-11-25 13:08:00 | Platelet derived microparticles formed in sepsis are a potent inducer of thrombin generation via phosphatidylserine exposure, and activation of both the intrinsic and extrinsic pathway of coagulation. | 28409836 |
| Type | IDs |
|---|---|
| Synonymous | Cf-2, Cf2, FII |
| Gene |
UniProtKB-ID:
THRB_MOUSE,
Q3TJ94_MOUSE
UniprotKB:
P19221,
Q3TJ94
UniParc:
UPI0000001942
EMBL:
AK167532,
X52308,
M81394,
BC013662
Ensembl:
ENSMUSG00000027249
KO:
mmu:14061
|
| Nucleutide sequences |
EMBL-CDS:
AAH13662.1,
AAA40435.1,
CAA36548.1,
BAE39601.1
Ensembl_TRS:
ENSMUST00000028681
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028681
RefSeq:
NP_034298.1,
XP_030103259.1,
XP_011237590.1
|
| Others |
UniRef100:
UniRef100_P19221
UniRef90:
UniRef90_P19221
UniRef50:
UniRef50_P00734
UniGene:
Mm.89048
CCDS:
CCDS16434.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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