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140579 Elmo2

140579

Elmo2

engulfment and cell motility 2

protein-coding

Mus musculus

基因描述

Type Description
Definition engulfment and cell motility 2

研究结论

Date Results Publications
2019-02-23 11:02:00 Study demonstrated that an evolutionarily conserved fragment in the C-terminal cytoplasmic tail of BAI-aGPCRs is specifically recognized by the RBD-ARR-ELMO (RAE) supramodule of the ELMO family scaffolds. The crystal structures of ELMO2-RAE and its complex with BAI1 uncover the molecular basis of BAI/ELMO interactions. 30604775
2017-10-07 13:02:00 Ilk and ELMO2 modulate recycling endosomes in keratinocytes undergoing intercellular adhesion mediated through cell-cell contacts, including E-cadherin-based adherens junctions. 27627840
2017-05-13 22:31:00 studies demonstrate that Elmo2 is a new regulator of insulin-dependent Glut4 membrane translocation through modulating Rac1 activity and Akt membrane compartmentalization. 27226625
2016-06-04 10:14:00 ELMO2-RhoG-ILK complex has a key role in integrin-independent stabilization of the microtubule network in differentiated keratinocytes. 25995380
2015-05-23 10:05:00 Collectively, our studies demonstrate that formation of an Elmo2.ClipR-59 complex plays an important role in myoblast fusion. 25572395

名称对应

Type IDs
Synonymous 1190002F24Rik, CED-12
Gene
UniProtKB-ID: ELMO2_MOUSE
UniprotKB: Q8BHL5
UniParc: UPI000019B4F9, UPI00000EB908, UPI00000019CC
EMBL: AL591430, AK045428, AK050823, AK038455, AF398884, BC023954, AK053574, AB093301, AK032033, AK033918, AK035710, AK047040, AK004448
Ensembl: ENSMUSG00000017670
KO: mmu:140579
Nucleutide sequences
EMBL-CDS: BAC35433.1, AAH23954.1, BAC34424.1, BAC32945.1, BAC41483.3, BAC27662.1, BAC30007.1, BAC29162.1, BAC32361.1, BAB23307.1, AAL14465.1, BAC28514.1
Ensembl_TRS: ENSMUST00000071699, ENSMUST00000074046, ENSMUST00000103088, ENSMUST00000094329, ENSMUST00000103091
Protein sequencees
Ensembl_PRO: ENSMUSP00000099380, ENSMUSP00000071619, ENSMUSP00000073691, ENSMUSP00000099377, ENSMUSP00000091887
RefSeq: XP_017170976.1, XP_036014169.1, NP_001289683.1, NP_525026.2, XP_011237588.1, NP_997589.1, XP_011237586.1, XP_036014165.1, XP_011237587.1, NP_001289681.1
Others
UniRef100: UniRef100_Q8BHL5
UniRef90: UniRef90_Q8BHL5
UniRef50: UniRef50_Q96JJ3
UniGene: Mm.35064
CCDS: CCDS17076.1, CCDS17075.1

全选

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