| Type | Description |
|---|---|
| Definition | EYA transcriptional coactivator and phosphatase 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 12:15:00 | these observations establish EYA3 as a disease-modifying target whose function in the pathophysiology of pulmonary arterial hypertension. | 31515519 |
| 2011-10-29 10:35:00 | Data showed that the 68-amino acid domain between positions 53 and 120 was necessary and sufficient for its threonine-phosphatase activity. | 21821028 |
| 2011-04-09 10:39:00 | Data demonstrate that Eya3 and its partner Six1 synergistically activate TSHbeta expression and that this activation is further enhanced by Tef and Hlf. | 21129973 |
| 2010-01-21 00:00:00 | There was no obvious defect in the eyes, ears and kidneys of Eya3 mutant mice. Homozygous mutants displayed decreased bone mineral content and shorter body length. | 19102749 |
| 2010-01-21 00:00:00 | Experiments performed in cultured Drosophila cells and in vitro indicate that Eyes absent has intrinsic protein tyrosine phosphatase activity and can autocatalytically dephosphorylate itself | 14628053 |
| Type | IDs |
|---|---|
| Synonymous | AI844637 |
| Gene |
UniProtKB-ID:
EYA3_MOUSE,
Q3TP96_MOUSE,
Q6P4T3_MOUSE
UniprotKB:
P97480,
Q3TP96,
Q6P4T3
UniParc:
UPI00005B20A0,
UPI00001930B0,
UPI00001F16B6,
UPI00001F16B5
EMBL:
U61112,
AL627130,
AJ007996,
U81604,
CH466552,
AK164591,
BC063259
Ensembl:
ENSMUSG00000028886
KO:
mmu:14050
|
| Nucleutide sequences |
EMBL-CDS:
AAB42068.1,
EDL30095.1,
CAA07819.1,
AAB48019.1,
BAE37841.1,
AAH63259.1
Ensembl_TRS:
ENSMUST00000020197,
ENSMUST00000079157,
ENSMUST00000180250,
ENSMUST00000081726
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000136812,
ENSMUSP00000020197,
ENSMUSP00000078157,
ENSMUSP00000080425
RefSeq:
XP_006538601.1,
XP_006538600.1,
XP_036019553.1,
NP_997596.1,
XP_036019552.1,
NP_034296.2,
NP_997592.1,
XP_006538603.1
|
| Others |
UniRef100:
UniRef100_P97480,
UniRef100_Q3TP96
UniRef90:
UniRef90_Q3TP96,
UniRef90_P97480
UniRef50:
UniRef50_P97480,
UniRef50_A0A2D4IYQ3
UniGene:
Mm.227733
CCDS:
CCDS18731.1,
CCDS18730.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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