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140494 Atp6v0a4

140494

Atp6v0a4

ATPase, H+ transporting, lysosomal V0 subunit A4

protein-coding

Mus musculus

基因描述

Type Description
Definition ATPase, H+ transporting, lysosomal V0 subunit A4

研究结论

Date Results Publications
2017-06-03 11:39:00 The identification of novel locations for the a4 subunit and other tissue-restricted subunits increases the range of unique subunit combinations making up the proton pump. 27368196
2013-09-14 11:37:00 The first detailed analysis of the structure and function of the auditory system in Atp6v0a4(-/-) knockout mice, is reported. 23065636
2013-03-02 13:07:00 V-ATPase a4 knockout mice suffer not only from severe acidosis but also from proximal tubule dysfunction with defective endocytic trafficking, proteinuria, phosphaturia and accumulation of lysosomal material. 22933323
2012-11-03 11:10:00 Atp6v0a4 knockout mouse is a model of distal renal tubular acidosis with hearing loss, with additional extrarenal phenotype 22872862
2010-01-21 00:00:00 Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase complex at these locations. 19214237

名称对应

Type IDs
Synonymous Atp6n1b, a4
Gene
UniProtKB-ID: VPP4_MOUSE, Q3UP55_MOUSE
UniprotKB: Q920R6, Q3UP55
UniParc: UPI00005AC235, UPI000000BB50
EMBL: AF435090, AK143790, BC046979, AB050903, AF326316
Ensembl: ENSMUSG00000038600
KO: mmu:140494
Nucleutide sequences
EMBL-CDS: AAN45855.1, AAL30435.1, BAB47243.1, AAH46979.1, BAE25542.1
Ensembl_TRS: ENSMUST00000040259, ENSMUST00000114908
Protein sequencees
Ensembl_PRO: ENSMUSP00000039381, ENSMUSP00000110558
RefSeq: NP_536715.3
Others
UniRef100: UniRef100_Q3UP55, UniRef100_Q920R6
UniRef90: UniRef90_Q920R6, UniRef90_Q3UP55
UniRef50: UniRef50_Q3UP55, UniRef50_Q9HBG4
UniGene: Mm.462308
CCDS: CCDS20010.1

全选

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研究热度

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