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140493 Kcnn3

140493

Kcnn3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

研究结论

Date Results Publications
2021-04-17 13:14:00 AMPK upregulates KCa2.3 channels and ameliorates endothelial dysfunction in diet-induced obese mice. 33186592
2020-01-11 10:52:00 Properties of SK3 channel-expressing PDGFRalpha (+) cells in the rodent urinary bladder 31326376
2019-09-21 11:15:00 Caveolae provide a key microdomain in renal collecting duct cells for coupling of TRPV4 with SK3, IK1, and BK that directly contributes to TRPV4-mediated Ca(2+) signaling in these domains. 30207167
2019-07-20 12:40:00 These findings demonstrate how Ca(2+) influx through TRPV4 channels can activate SK channels in PDGFRalpha(+) cells and prevent bladder overactivity during filling. 28947806
2018-12-22 12:00:00 the present study shows that KCa2.3 channels are located in the apical plasma membrane of endothelial cells, and occasionally at inter-endothelial junctions of the corpus cavernosum. We found that down-regulation of these channels increases norepinephrine contraction in corpus cavernosum strips, and it seems associated with erectile dysfunction. 28630432

名称对应

Type IDs
Synonymous KCa2.3, SK3, SKCA3
Gene
UniProtKB-ID: KCNN3_MOUSE
UniprotKB: P58391
UniParc: UPI000019280F
EMBL: AC171273, BC106769, BC106770, AF357241, AC166364, AK137738
Ensembl: ENSMUSG00000000794
KO: mmu:140493
Nucleutide sequences
EMBL-CDS: AAI06770.1, AAK48902.1, AAI06771.1, BAE23484.1
Ensembl_TRS: ENSMUST00000000811
Protein sequencees
Ensembl_PRO: ENSMUSP00000000811
RefSeq: NP_536714.2
Others
UniRef100: UniRef100_P58391
UniRef90: UniRef90_P70605
UniRef50: UniRef50_P70605
UniGene: Mm.120250
CCDS: CCDS38495.1

全选

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研究热度

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