| Type | Description |
|---|---|
| Definition | EYA transcriptional coactivator and phosphatase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-07 11:22:00 | Notch is regulated by the threonine phosphatase activity of Eya1. Eya1 dephosphorylates p-threonine-2122 of the Notch1 intracellular domain (Notch1 ICD), which increases the stability of Notch1 ICD and maintains Notch signaling activity in the non-neuronal epibranchial placodal cells. | 29140246 |
| 2016-03-19 11:54:00 | data support a model where Eya-Six may form a complex to regulate nephron progenitor cell development before metanephric specification and are critical mesenchymal factors for inducing nephric duct development. | 25903664 |
| 2015-06-20 10:37:00 | Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis | 25816987 |
| 2015-02-14 11:22:00 | results reveal a functional link between Eya1, Six2, and Myc in driving the expansion and maintenance of the multipotent progenitors during nephrogenesis | 25458011 |
| 2014-10-11 12:49:00 | BOR syndrome-associated Eya1 missense mutations S454P, L472R, and L550P lead to enhanced proteasomal degradation of the Eya1 protein. | 24489909 |
| Type | IDs |
|---|---|
| Synonymous | bor |
| Gene |
UniProtKB-ID:
EYA1_MOUSE,
Q8C9D0_MOUSE,
Q6PAJ8_MOUSE,
F6YST4_MOUSE
UniprotKB:
P97767,
Q8C9D0,
Q6PAJ8,
F6YST4
UniParc:
UPI00000E9784,
UPI00015DF5FC,
UPI000154AD69,
UPI0000675122,
UPI00001DFBD3
EMBL:
Y10263,
AF097544,
BC060260,
AJ007995,
AK042412,
AC119875,
AC156988,
CH466536,
U61110
Ensembl:
ENSMUSG00000025932
KO:
mmu:14048
|
| Nucleutide sequences |
EMBL-CDS:
EDL14327.1,
AAD19355.1,
CAA07818.1,
AAB48017.1,
CAA71312.1,
BAC31251.1,
AAH60260.1
Ensembl_TRS:
ENSMUST00000190337,
ENSMUST00000027066,
ENSMUST00000080664,
ENSMUST00000168081
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000141112,
ENSMUSP00000027066,
ENSMUSP00000079493,
ENSMUSP00000126383
RefSeq:
XP_017170903.1,
NP_034294.2,
XP_036015537.1,
XP_030103330.1,
XP_017170837.1,
XP_006495514.1,
XP_011236646.1,
XP_036015555.1,
XP_006495509.1,
XP_011236648.1,
NP_001239121.1,
NP_001297388.1,
XP_036015560.1,
XP_017170870.1,
XP_017170911.1,
XP_006495515.1,
XP_036015568.1
|
| Others |
UniRef100:
UniRef100_Q8C9D0,
UniRef100_F6YST4,
UniRef100_P97767
UniRef90:
UniRef90_P97767-2,
UniRef90_P97767
UniRef50:
UniRef50_P97767-2,
UniRef50_P97767
UniGene:
Mm.250185
CCDS:
CCDS78545.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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