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140477 Dmbx1

140477

Dmbx1

diencephalon/mesencephalon homeobox 1

protein-coding

Mus musculus

基因描述

Type Description
Definition diencephalon/mesencephalon homeobox 1

研究结论

Date Results Publications
2020-07-11 10:22:00 ATX genetic deletion from CD11b+ cells attenuated the severity of experimental autoimmune encephalomyelitis (EAE), thus proposing a pathogenic role for the ATX/LPA axis in neuroinflammatory disorders. 32240164
2017-07-01 10:52:00 The crystal structure of mouse ATX in complex with an anti-ATX aptamer. 27043297
2016-05-21 12:40:00 Data (including data from studies in transgenic/knockout mice) suggest that expression in adult brain neurons (especially in parabrachial nucleus) of both Dmbx1 and AgRP (agouti-related peptide) is important in appetite regulation leading to leanness. 26505115
2010-01-21 00:00:00 Dmbx1 is essential for various actions of agouti-related protein and plays a role in normal regulation of energy homeostasis and behavior 17873059
2010-01-21 00:00:00 Otx3/Dmbx1 represses Otx2-mediated transcription in the developing brain 15890343

名称对应

Type IDs
Synonymous Atx, Cdmx, Mbx, Otx3
Gene
UniProtKB-ID: DMBX1_MOUSE
UniprotKB: Q91ZK4
UniParc: UPI00000E750F, UPI00000E7F90
EMBL: AF499446, AF421858, AB037698, AF421857, AF461039, AL627105, AF448118, AF463513, BC050912
Ensembl: ENSMUSG00000028707
KO: mmu:140477
Nucleutide sequences
EMBL-CDS: AAM78514.1, AAH50912.1, AAL66343.1, BAC00919.1, AAN76724.1, AAL30509.1, AAL30508.1, AAL68836.1
Ensembl_TRS: ENSMUST00000124071, ENSMUST00000084338, ENSMUST00000064806
Protein sequencees
Ensembl_PRO: ENSMUSP00000081366, ENSMUSP00000120320, ENSMUSP00000134457
RefSeq: XP_017175448.1, NP_001020738.1, XP_017175447.1, XP_011238738.1, XP_030109053.1, NP_570935.3, XP_017175446.1
Others
UniRef100: UniRef100_Q91ZK4
UniRef90: UniRef90_Q91ZK4
UniRef50: UniRef50_Q91ZK4
UniGene: Mm.213206, Mm.413175
CCDS: CCDS18500.1

全选

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