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140462 ASB9

140462

ASB9

ankyrin repeat and SOCS box containing 9

protein-coding

Homo sapiens

基因描述

Type Description
Definition ankyrin repeat and SOCS box containing 9

研究结论

Date Results Publications
2020-08-22 15:28:00 Structure and dynamics of the ASB9 CUL-RING E3 Ligase. 32513959
2017-10-07 11:58:00 Model of ASB9 in complex with its substrate, creatine kinase, reveals a mechanism for dynamic ubiquitin transfer. 27396830
2015-05-02 12:54:00 Molecular docking yielded a structural model consistent with all of the data that suggested the N-terminal residues of ASB9(1-252) may lie in one CK active site. This model was corroborated by enzymatic activity assays and mutational analysis. 25654263
2014-01-04 10:48:00 ASB9 is unstable alone but forms a stable ternary complex with EloBC that binds with high affinity to the Cullin 5 N-terminal domain. 23837592
2012-08-18 10:39:00 His103 and Phe107 in hASB9-2 are essential for binding to CKB. 22418839

名称对应

Type IDs
Gene
UniProtKB-ID: ASB9_HUMAN, A0A024RBW7_HUMAN, A0A024RBZ4_HUMAN, A0A024RBW2_HUMAN
UniprotKB: Q96DX5, A0A024RBW7, A0A024RBZ4, A0A024RBW2
UniParc: UPI000006E235, UPI00001260ED, UPI000002A407
EMBL: AK292270, HM005337, CH471074, BC013172, AL080091, BC001244, AK000643
Ensembl: ENSG00000102048
KO: hsa:140462
Nucleutide sequences
EMBL-CDS: AAH01244.1, EAW98874.1, EAW98871.1, AAH13172.1, BAA91302.1, CAB45706.2, BAF84959.1, AEE60937.1, EAW98876.1, EAW98870.1, EAW98875.1, EAW98873.1
Gene_ORFName: hCG_15754, hCG_15754, hCG_15754
Ensembl_TRS: ENST00000546332, ENST00000380483, ENST00000380488, ENST00000380485
Protein sequencees
Ensembl_PRO: ENSP00000369855, ENSP00000369852, ENSP00000438943, ENSP00000369850
RefSeq: NP_001026909.1, XP_016884772.1, XP_016884775.1, XP_011543762.1, XP_024308109.1, XP_016884774.1, XP_011543760.1, NP_001162002.1, XP_005274503.1, NP_076992.1, NP_001162003.1, XP_016884773.1
Others
UniRef100: UniRef100_A0A024RBZ4, UniRef100_Q96DX5, UniRef100_A0A024RBW2
UniRef90: UniRef90_Q96DX5, UniRef90_Q7Z4A2
UniRef50: UniRef50_Q7Z4A2, UniRef50_Q96DX5
UniGene: Hs.19404
CCDS: CCDS35208.1, CCDS55372.1, CCDS14163.1

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