| Type | Description |
|---|---|
| Definition | mucin 17, cell surface associated |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 12:16:00 | Overexpression and increased presentation at the plasma membrane of wild-type MUC17 and its phosphodeficient variant MUC17 S-4492A protected Caco-2 cells against adhesion of enteropathogenic Escherichia coli, indicating that C-terminal phosphorylation of MUC17 may play a functional role in epithelial cell protection. | 31387973 |
| 2019-12-14 10:45:00 | MUC17 inactivated NFkappaB to inhibit gastric cancer cell proliferation in response to pro-inflammatory cytokines. The MUC17 function was dependent on its conserved epidermal growth factor domain and on downstream sequences to enable its interaction with myosin-9, resulting in a regulatory feedback loop between myosin-9, p53, and RhoA, and then activation of p38 to negatively regulate the NFkappaB pathway in gastric ca... | 31262330 |
| 2015-10-24 11:30:00 | MUC17 polymorphisms are involved in endometriosis development and the associated infertility in the Taiwanese population. | 26285705 |
| 2013-10-26 10:59:00 | Carbachol stimulated enterocyte MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment. | 23784542 |
| 2013-05-04 12:29:00 | The HIF1alpha-mediated hypoxic signal pathway contributes to MUC17 expression, and DNA methylation of hypoxia responsive element could be a determinant of the hypoxic inducibility of MUC17 in pancreatic cancer cells. | 22970168 |
| Type | IDs |
|---|---|
| Synonymous | MUC-17, MUC-3, MUC3 |
| Gene |
UniProtKB-ID:
MUC17_HUMAN
UniprotKB:
Q685J3
UniParc:
UPI0000D5BB56,
UPI0001D147A6
EMBL:
AF430017,
AJ606307,
AF016693,
AC105446,
AJ606308
Ensembl:
ENSG00000169876
KO:
hsa:140453
|
| Nucleutide sequences |
EMBL-CDS:
CAE54436.1,
AAB71686.1,
CAE54435.1,
AAL89737.1
Ensembl_TRS:
ENST00000306151
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000302716
RefSeq:
NP_001035194.1
|
| Others |
UniRef100:
UniRef100_Q685J3
UniRef90:
UniRef90_Q685J3
UniRef50:
UniRef50_Q685J3
UniGene:
Hs.271819
CCDS:
CCDS34711.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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