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14043 Ext2

14043

Ext2

exostoses (multiple) 2

protein-coding

Mus musculus

基因描述

Type Description
Definition exostoses (multiple) 2

研究结论

Date Results Publications
2020-06-27 12:40:00 Using mouse embryonic stem cell-derived mosaic tissues with compartments that lack Exostosin1 and Exostosin2, or Glypican5, it has been shown that Shh accumulates around its source cells when they are surrounded by cells that have a mutated extracellular matrix. 30977233
2018-06-09 10:08:00 Let-7b-mediated suppression of initiation codon depends on the length of 5'-UTR of EXT2 mRNA and its suppression is inhibited in the presence of polyamines. 27650265
2015-10-10 11:26:00 Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation. 25468659
2011-08-13 11:36:00 The study indicates that formation of stereotypic exostoses requires a significant, but not complete, loss of Ext expression. 21310272
2010-01-21 00:00:00 NDST1 competes with EXT1 for binding to EXT2. 18337501

名称对应

Type IDs
Synonymous AI893565
Gene
UniProtKB-ID: EXT2_MOUSE, Q3UDB5_MOUSE
UniprotKB: P70428, Q3UDB5
UniParc: UPI0000022B0E, UPI00005AC980
EMBL: BC006597, AL732493, AK164342, CH466519, AK150155, U72141, U67837, AL732472
Ensembl: ENSMUSG00000027198
KO: mmu:14043
Nucleutide sequences
EMBL-CDS: AAB17006.1, EDL27629.1, AAC53143.1, BAE37749.1, AAH06597.1, BAE29346.1
Ensembl_TRS: ENSMUST00000028623
Protein sequencees
Ensembl_PRO: ENSMUSP00000028623
RefSeq: NP_001342005.1, XP_006498793.1, NP_001342004.1, NP_034293.2, XP_006498794.1, XP_036014154.1
Others
UniRef100: UniRef100_P70428
UniRef90: UniRef90_P70428
UniRef50: UniRef50_P70428
UniGene: Mm.4336
CCDS: CCDS16456.1

全选

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