| Type | Description |
|---|---|
| Definition | drosha, ribonuclease type III |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 11:06:00 | Comparison of the miRNA profiles between wildtype and SUN1 null myotubes identified a cluster of miRNAs encoded by a non-translated retrotransposon-like one antisense (Rtl1as) transcript that are decreased in the WT myoblasts due to SUN1 inhibition of Drosha | 31686651 |
| 2019-11-30 12:16:00 | Drosha plays a critical role in the survival of dopaminergic neurons. | 29880811 |
| 2019-10-26 10:12:00 | Administration of bovine milk exosomes failed to rescue Drosha homozygous knockout mice, presumably due to low bioavailability or lack of essential microRNAs | 30054561 |
| 2019-06-08 11:50:00 | Study in mouse lines with either a targeted deletion of Drosha or an inducible expression of human carrying a Wilms tumor (WT)-specific E1147K mutation that acts in a dominant negative manner underscores the importance of a viable self-renewing progenitor pool for kidney development, but there was no evidence of WT formation through impaired Dduanyu1670HA function. | 30367465 |
| 2019-03-23 12:41:00 | Mice lacking Drosha in the vascular endothelium developed a vascular phenotype resembling hereditary hemorrhagic telangiectasia that included dilated and disorganized vasculature, arteriovenous fistulae, and hemorrhages. | 29339534 |
| Type | IDs |
|---|---|
| Synonymous | 1110013A17Rik, AI874853, Etohi2, Rn3, Rnasen |
| Gene |
UniProtKB-ID:
RNC_MOUSE
UniprotKB:
Q5HZJ0
UniParc:
UPI00004294BA
EMBL:
AK148640,
BC088999,
AK144147
Ensembl:
ENSMUSG00000022191
KO:
mmu:14000
|
| Nucleutide sequences |
EMBL-CDS:
BAE28629.1,
AAH88999.1,
BAE25729.1
Ensembl_TRS:
ENSMUST00000169061,
ENSMUST00000090292
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129279,
ENSMUSP00000087762
RefSeq:
NP_081075.3,
NP_001123621.1,
XP_006520084.1
|
| Others |
UniRef100:
UniRef100_Q5HZJ0
UniRef90:
UniRef90_Q5HZJ0
UniRef50:
UniRef50_Q9NRR4
UniGene:
Mm.293142
CCDS:
CCDS49583.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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