| Type | Description |
|---|---|
| Definition | CRK proto-oncogene, adaptor protein |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:38:00 | Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial-mesenchymal transition and colorectal cancer aggressiveness. | 32147820 |
| 2021-01-09 13:26:00 | MiR-194-5p inhibited metastasis and EMT of nephroblastoma cells through targeting Crk. | 31889432 |
| 2020-10-24 14:00:00 | Signaling adaptor protein Crk is involved in malignant feature of pancreatic cancer associated with phosphorylation of c-Met. | 32005519 |
| 2020-07-18 12:21:00 | ACAP4 physically interacts with CrkII. Functional characterization showed that the interaction is required for the recruitment of ACAP4 to the plasma membrane where ACAP4 functions to regulate the recycling of the signal transducer integrin beta1. | 31182282 |
| 2020-04-04 12:02:00 | by binding to CrkII, PEAK3 prevents the formation of CrkII-dependent membrane ruffling. | 31311869 |
| Type | IDs |
|---|---|
| Synonymous | CRKII, p38 |
| Gene |
UniProtKB-ID:
CRK_HUMAN,
L7RT18_HUMAN,
A0A0S2Z3K9_HUMAN,
A0A0S2Z3Q4_HUMAN
UniprotKB:
P46108,
L7RT18,
A0A0S2Z3K9,
A0A0S2Z3Q4
UniParc:
UPI0000071225,
UPI000007290B
EMBL:
AC100748,
BC009837,
AC032044,
BT007277,
S65701,
EU332838,
D10656,
KU177997,
JX512441,
BC008506,
AK291060,
KU177996,
CH471108,
BC001718
Ensembl:
ENSG00000167193
KO:
hsa:1398
|
| Nucleutide sequences |
EMBL-CDS:
BAF83749.1,
AAH01718.1,
EAW90625.1,
ABY87527.1,
AAH08506.1,
AAH09837.1,
AAB28213.1,
AAP35941.1,
EAW90621.1,
EAW90624.1,
BAA01505.1,
AGC09588.1,
ALQ33455.1,
ALQ33454.1
Ensembl_TRS:
ENST00000300574,
ENST00000398970
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000300574,
ENSP00000381942
RefSeq:
NP_058431.2,
NP_005197.3
|
| Others |
UniRef100:
UniRef100_P46108,
UniRef100_A0A0S2Z3K9
UniRef90:
UniRef90_Q8JZR2,
UniRef90_P46108
UniRef50:
UniRef50_P46108,
UniRef50_A0A2I3MEC4
UniGene:
Hs.461896
CCDS:
CCDS45561.1,
CCDS11002.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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