| Type | Description |
|---|---|
| Definition | FUN14 domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:30:00 | Silencing FUNDC1 alleviates chronic obstructive pulmonary disease by inhibiting mitochondrial autophagy and bronchial epithelium cell apoptosis under hypoxic environment. | 31237014 |
| 2020-05-23 11:25:00 | accumulates in most hepatocellular carcinomas | 30053328 |
| 2019-07-13 10:55:00 | Elevated FUNDC1 levelcould stimulate human breast cancer proliferation and migration via Ca2+influxas well as NFATC1 activation and translocation into the nucleus, whichfurther binds and activates BMI1 transcription. The positive relationshipbetween FUNDC1 and BMI1 expression further predicts worse progres-sion of breast cancer. | 30803933 |
| 2018-04-28 11:17:00 | Our data suggested that FUNDC1 can be used as a prognostic biomarker in patients with cervical cancer, and may be a new therapeutic target to improve the antitumor effects of chemoradiotherapy. | 28719148 |
| 2017-11-18 10:07:00 | phosphorylation of Tyr18 of FUNDC1 serves as a molecular switch for mitophagy. | 27653272 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FUND1_HUMAN
UniprotKB:
Q8IVP5
UniParc:
UPI000004A05A
EMBL:
AL136137,
BC042813,
BC035015,
AL022163
Ensembl:
ENSG00000069509
KO:
hsa:139341
|
| Nucleutide sequences |
EMBL-CDS:
AAH42813.1,
AAH35015.1
Ensembl_TRS:
ENST00000378045
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367284
RefSeq:
NP_776155.1
|
| Others |
UniRef100:
UniRef100_Q8IVP5
UniRef90:
UniRef90_Q8IVP5
UniRef50:
UniRef50_Q8IVP5
UniGene:
Hs.7549
CCDS:
CCDS14263.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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