| Type | Description |
|---|---|
| Definition | excision repair cross-complementing rodent repair deficiency, complementation group 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-02-27 11:44:00 | Results describe a recessive cataract caused by a mutation in the Xpd/Ercc2 gene and demonstrate the importance of the gene not only for lens fiber cell differentiation, but also for the sensitivity to ionizing radiation. | 25951169 |
| 2013-03-30 13:09:00 | Compound TTD/XPCS heterozygosity partially rescues metabolic phenotype associated with homozygous XPD alleles. TTD allele dominates over XPCS allele in measures of UV-sensitivity. | 23046824 |
| 2010-01-21 00:00:00 | XPCS with a G602D-encoding mutation in the Xpd helicase gene is the most skin cancer-prone NER model to date, and it shows an unusual NER dysfunction that is likely responsible for this susceptibility | 16904611 |
| 2010-01-21 00:00:00 | New pathology features support the premature aging phenotype of Xpd(TTD) mutant mice and further strengthen the link between DNA damage, DNA repair and aging. | 16115803 |
| 2010-01-21 00:00:00 | a variety of biallelic effects on organismal phenotype which attributes to combinations of recessive Xpd alleles | 17020410 |
| Type | IDs |
|---|---|
| Synonymous | AA407812, AU020867, AW240756, CXPD, Ercc-2, Mhdarco15, RCO015, XPD |
| Gene |
UniProtKB-ID:
ERCC2_MOUSE
UniprotKB:
O08811
UniParc:
UPI00000E9E1F
EMBL:
U97572,
AK082761,
CH466639,
AK004652
Ensembl:
ENSMUSG00000030400
KO:
mmu:13871
|
| Nucleutide sequences |
EMBL-CDS:
BAB23443.1,
AAB58296.1,
BAC38607.1,
EDL23140.1
Ensembl_TRS:
ENSMUST00000062831
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000054380
RefSeq:
NP_031975.2,
NP_001350910.1
|
| Others |
UniRef100:
UniRef100_O08811
UniRef90:
UniRef90_P18074
UniRef50:
UniRef50_P18074
UniGene:
Mm.36524
CCDS:
CCDS20900.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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