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13852 Stx2

13852

Stx2

syntaxin 2

protein-coding

Mus musculus

基因描述

Type Description
Definition syntaxin 2

研究结论

Date Results Publications
2019-06-01 11:11:00 he patient showed azoospermia, relatively small testes, and a mildly elevated follicle stimulating hormone level, but no additional clinical features. Testicular histology of the patient showed universal maturation arrest and multinucleated spermatocytes, which have also been observed in mice lacking Stx2. PCR-based cDNA screening revealed wildtype STX2 expression in various tissues including the testis 29570232
2017-06-24 11:15:00 Syn-2 knockout mice exhibited paradoxical superior glucose homeostasis resulting from an enhanced insulin secretion. The increase in insulin exocytosis was attributed mainly to an enhanced recruitment of the larger pool of newcomer secretory granules (SGs) that undergoes no residence time on plasma membrane before fusion and, to a lesser extent, also the predocked SGs. 28115395
2016-11-12 12:02:00 The selectivity in syntaxin binding and apical protein redistribution further suggests that rab17 and syntaxin 2 mediate fusion of transcytotic vesicles at the apical surface. 26957544
2013-12-07 11:27:00 It was concluded that Epim deletion inhibits polyposis in Apcmin/+ mice, associated with increased mucosal TGF-beta signaling and decreased myofibroblast HGF expression and secretion. 23886856
2013-11-16 11:20:00 Overexpression of Epim expression is associated with mammary carcinoma. 23867473

名称对应

Type IDs
Synonymous AW538950, Epim, G1-536-1, Syn-2, repro34
Gene
UniProtKB-ID: Q80W45_MOUSE, Q3TJ55_MOUSE
UniprotKB: Q80W45, Q3TJ55
UniParc: UPI000000B995, UPI000014E118
EMBL: BC046279, AC110566, AK146462, AK167577
Ensembl: ENSMUSG00000029428
KO: mmu:13852
Nucleutide sequences
EMBL-CDS: AAH46279.1, BAE27190.1, BAE39640.1
Ensembl_TRS: ENSMUST00000031378, ENSMUST00000100680
Protein sequencees
Ensembl_PRO: ENSMUSP00000031378, ENSMUSP00000098247
RefSeq: NP_001345951.1, XP_006504339.1, NP_001272963.1, NP_001272962.1, NP_031967.2
Others
UniRef100: UniRef100_Q3TJ55, UniRef100_Q80W45
UniRef90: UniRef90_P50279-2, UniRef90_P50279
UniRef50: UniRef50_P32856-2, UniRef50_P32856
UniGene: Mm.260716

全选

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