| Type | Description |
|---|---|
| Definition | glutamyl aminopeptidase |
| Date | Results | Publications |
|---|---|---|
| 2015-09-26 21:45:00 | de-regulation of both PITX2 and ENPEP could contribute to an increased risk of atrial fibrillation in carriers of disease-associated variants. | 25888893 |
| 2014-05-31 11:21:00 | Demonstrate a novel role of APA in ANG-(1-7) metabolism and suggest that the upregulation of APA, which occurs after myocardial infarction, may deprive the heart of cardioprotective ANG-(1-7). | 24464749 |
| 2011-01-01 11:24:00 | Ischemia-induced angiogenesis is impaired in APA-KO mice partly through decreased HIF-1alpha stability by proteasomal degradation and subsequent suppression of HIF-1alpha-driven target protein expression such as growth factors. | 20946870 |
| 2010-01-21 00:00:00 | Replacement of active site residue glutamate-215 of aminopeptidase A with aspartate or alanine leads to a strong decrease in the rate of hydrolysis of the synthetic substrate alpha-L-glutamyl-beta-naphthylamide. | 14674752 |
| 2010-01-21 00:00:00 | dietary fatty acids affect activity in moue testis | 11903661 |
| Type | IDs |
|---|---|
| Synonymous | 6030431M22Rik, APA, Bp-1/6C3, Ly-51, Ly51 |
| Gene |
UniProtKB-ID:
AMPE_MOUSE,
Q8CD51_MOUSE,
Q52JJ6_MOUSE,
Q6P3C1_MOUSE
UniprotKB:
P16406,
Q8CD51,
Q52JJ6,
Q6P3C1
UniParc:
UPI00000E92BB,
UPI0000029C01,
UPI000022832D
EMBL:
BC127060,
M29961,
BC064061,
AK146808,
DQ000292,
AK031439
Ensembl:
ENSMUSG00000028024
KO:
mmu:13809
|
| Nucleutide sequences |
EMBL-CDS:
AAB47732.1,
BAC27405.1,
AAY16106.1,
AAI27061.1,
BAE27448.1,
AAH64061.1
Ensembl_TRS:
ENSMUST00000029658
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029658
RefSeq:
NP_031960.1
|
| Others |
UniRef100:
UniRef100_Q6P3C1,
UniRef100_P16406
UniRef90:
UniRef90_Q6P3C1,
UniRef90_P16406
UniRef50:
UniRef50_Q07075,
UniRef50_Q6P3C1
UniGene:
Mm.1193
CCDS:
CCDS17831.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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