| Type | Description |
|---|---|
| Definition | endonuclease G |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:11:00 | Crystal structure of the mouse endonuclease G. | 32192768 |
| 2020-07-11 11:02:00 | The specificity of endonuclease G for 5-hydroxymethylcytosine (5hmC) and Holliday junctions derives from structural adaptations that distinguish the vertebrate from the invertebrate enzyme, thereby thereby supporting a role for 5hmC in recombination processes. | 32095813 |
| 2018-10-13 11:50:00 | These results support the involvement of redox signaling in the control of cardiomyocyte growth by ENDOG and suggest a pathway relating mtDNA content to the regulation of cell growth probably involving humanin, which prevents reactive oxygen radicals accumulation and hypertrophy induced by Endog deficiency. | 29502044 |
| 2017-11-04 12:46:00 | Deficiency of AKT2 in myocardium results in diminished MEF2A abundance, which induced decreased size of cardiomyocytes. We additionally confirmed that EndoG, which is also regulated by AKT2, is a suppressor of MEF2A in myocardium. | 28965945 |
| 2017-06-03 12:20:00 | increased browning of white adipose tissue elicited by the lack of EndoG was associated with a better glucose tolerance and reduced fat mass | 27547848 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
NUCG_MOUSE,
Q3UN47_MOUSE
UniprotKB:
O08600,
Q3UN47
UniParc:
UPI0000001A7E
EMBL:
X99395,
AB012108,
AK144459,
X99394,
BC030177
Ensembl:
ENSMUSG00000015337
KO:
mmu:13804
|
| Nucleutide sequences |
EMBL-CDS:
BAA28168.1,
CAA67769.1,
AAH30177.1,
CAA67768.1,
BAE25900.1
Ensembl_TRS:
ENSMUST00000015481
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000015481
RefSeq:
NP_031957.1
|
| Others |
UniRef100:
UniRef100_O08600
UniRef90:
UniRef90_O08600
UniRef50:
UniRef50_O08600
UniGene:
Mm.474473
CCDS:
CCDS15872.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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