| Type | Description |
|---|---|
| Definition | engrailed 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:41:00 | Morphological alterations of the reticular thalamic nucleus in Engrailed-2 knockout mice. | 31972897 |
| 2021-03-27 14:40:00 | Altered Expression of GABAergic Markers in the Forebrain of Young and Adult Engrailed-2 Knockout Mice. | 32244845 |
| 2020-01-11 12:18:00 | En2 is expressed in all three nuclear layers of the adult retina. When compared to age-matched En2(+/+) controls, En2(-/-) adult retinas showed a significant decrease in the number of calbindin(+) horizontal cells, and a significant increase in calbindin(+) amacrine/ganglion cells. In addition, En2(-/-) adult mice showed a significant reduction of photoreceptor (rhodopsin) and bipolar cell (Pcp2, markers. | 30980901 |
| 2020-01-04 10:30:00 | En2 (-/-) mice showed reduced functional connectivity in the somatosensory cortex, which was paralleled by fear behavior, reduced activation of somatosensory cortex, and increased activation of the basolateral amygdala in response to repeated whisker stimulation. | 30593497 |
| 2019-05-04 10:27:00 | data indicate that deficits in En2 can produce sensory impairments that can have a measurable impact on taste, particularly salt taste. | 29953887 |
| Type | IDs |
|---|---|
| Synonymous | BB131122, En-2, mo-En-2 |
| Gene |
UniProtKB-ID:
HME2_MOUSE,
Q3TZM2_MOUSE
UniprotKB:
P09066,
Q3TZM2
UniParc:
UPI0000023EAA
EMBL:
L12705,
AK157766,
L12704,
Y00203
Ensembl:
ENSMUSG00000039095
KO:
mmu:13799
|
| Nucleutide sequences |
EMBL-CDS:
AAA53527.1,
CAA68362.1,
BAE34186.1
Ensembl_TRS:
ENSMUST00000036177
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036761
RefSeq:
NP_034264.1
|
| Others |
UniRef100:
UniRef100_P09066
UniRef90:
UniRef90_P09066
UniRef50:
UniRef50_P09066
UniGene:
Mm.4298
CCDS:
CCDS19143.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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