| Type | Description |
|---|---|
| Definition | engrailed 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 10:06:00 | Following intrastriatal injection of pre-formed alpha-synuclein fibrils, absence of an En1 allele leads to additional aggregation of pathological alpha-syn, potentially due to En1-loss mediated nigrostriatal impairment | 30932894 |
| 2019-04-20 12:21:00 | LINE-1 overexpression triggers oxidative stress-induced DNA strand breaks and that an Engrailed-1 adult function is to protect mesencephalic dopaminergic neurons through the repression of LINE-1 expression. | 29941661 |
| 2018-05-12 10:18:00 | C57Bl/6-engrailed-1 (En1+/-) mice do not display the neurodegenerative phenotype, suggesting that susceptibility to En1 heterozygosity is genetically regulated. | 27550741 |
| 2017-10-14 12:05:00 | En1 is important for ventral nuclei of the lateral lemniscus neuron development and survival. | 26914477 |
| 2017-10-14 10:56:00 | in absence of En1 and Pitx3, only a limited number of Mesodiencephalic dopaminergic neurons are present in mouse embryo. | 28800615 |
| Type | IDs |
|---|---|
| Synonymous | En-1, Mo-en.1, engrailed-1 |
| Gene |
UniProtKB-ID:
HME1_MOUSE,
Q3USA2_MOUSE
UniprotKB:
P09065,
Q3USA2
UniParc:
UPI000024E10E,
UPI00005ABFD7
EMBL:
Y00201,
L12703,
AK140634,
AK140408
Ensembl:
ENSMUSG00000058665
KO:
mmu:13798
|
| Nucleutide sequences |
EMBL-CDS:
CAA68361.1,
AAA03660.2,
BAE24375.1,
BAE24431.1
Ensembl_TRS:
ENSMUST00000079721
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000078659
RefSeq:
NP_034263.2
|
| Others |
UniRef100:
UniRef100_Q3USA2,
UniRef100_P09065
UniRef90:
UniRef90_P09065,
UniRef90_Q3USA2
UniRef50:
UniRef50_P09065,
UniRef50_Q3USA2
UniGene:
Mm.2657
CCDS:
CCDS15235.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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