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137970 UNC5D

137970

UNC5D

unc-5 netrin receptor D

protein-coding

Homo sapiens

基因描述

Type Description
Definition unc-5 netrin receptor D

研究结论

Date Results Publications
2019-04-20 11:18:00 these results suggested that UNC5D as a novel putative metastatic suppressor gene that is commonly down-regulated by hypermethylation in PCa. 30632669
2017-11-11 12:48:00 The authors identified a locus on chromosome 8, containing UNC5D, and demonstrated evidence of its genome-wide significance with mental composite scores. Within this locus, the joint effects of two independent single nucleotide polymorphisms had a p-value of 4.38 x 10(-9) for mental composite scores. 28754176
2015-01-10 12:27:00 Unc5D is thus a newly identified transcriptional target of proapoptotic p53 and may also act upstream of p53 to induce p53dependent apoptosis by phosphorylation at ser15. 24691657
2014-08-23 10:54:00 the dependence receptor UNC5H4 may act as a putative tumor suppressor in neuroblastoma. 24519068
2014-01-11 11:15:00 UNC5D is a functional tumor suppressor that is frequently downregulated in RCCs due to promoter hypermethylation and LOH. 23589179

名称对应

Type IDs
Synonymous PRO34692, Unc5h4
Gene
UniProtKB-ID: UNC5D_HUMAN, C9J1I0_HUMAN, H7BXJ2_HUMAN
UniprotKB: Q6UXZ4, C9J1I0, H7BXJ2
UniParc: UPI00001D6915, UPI00004FBDBA, UPI000198CCAE, UPI000006EE8A
EMBL: AC013302, AC090740, AB055056, AC104049, AC012215, AY358147, AC105230, AC099685
Ensembl: ENSG00000156687
KO: hsa:137970
Nucleutide sequences
EMBL-CDS: BAB83663.1, AAQ88514.1
Gene_ORFName: UNQ6012/PRO34692
Ensembl_TRS: ENST00000404895, ENST00000453357, ENST00000420357, ENST00000287272
Protein sequencees
Ensembl_PRO: ENSP00000385143, ENSP00000394303, ENSP00000392739, ENSP00000287272
RefSeq: XP_011542702.1, NP_001309747.1, XP_011542703.1, XP_011542704.1, XP_016868537.1, XP_011542705.1, XP_016868535.1, XP_016868538.1, NP_543148.2, XP_016868534.1, XP_016868539.1, XP_016868536.1, XP_011542706.1, XP_016868533.1
Others
UniRef100: UniRef100_H7BXJ2, UniRef100_C9J1I0, UniRef100_Q6UXZ4
UniRef90: UniRef90_Q6UXZ4
UniRef50: UniRef50_Q8K1S2
UniGene: Hs.238889
CCDS: CCDS6093.2, CCDS83279.1

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