| Type | Description |
|---|---|
| Definition | alcohol dehydrogenase iron containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 10:53:00 | data support the hypothesis that ADHFE1 and MYC signaling contribute to D-2HG accumulation in breast tumors and show that D-2HG is an oncogenic metabolite and potential driver of disease progression. | 29202474 |
| 2014-12-20 10:15:00 | These results demonstrate that the promoter hypermethylation of ADHFE1 is frequently present in CRC and alcohol induces methylation-mediated down expression of ADHFE1 and proliferation of CRC cells. | 24886599 |
| 2013-09-21 13:21:00 | ADHFE1 has an important role of differentiation in CRC, as well as normal colorectal mucosa and embryonic developmental processes. | 23517143 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2010-01-21 00:00:00 | cloned and characterized an iron-activated alcohol dehydrogenase gene, Fe-containing alcohol dehydrogenase 1 (ADHFe1) | 12592711 |
| Type | IDs |
|---|---|
| Synonymous | ADH8, HMFT2263, HOT |
| Gene |
UniProtKB-ID:
HOT_HUMAN
UniprotKB:
Q8IWW8
UniParc:
UPI0000231C60,
UPI000004966C,
UPI0000210795,
UPI00004576AF
EMBL:
CH471068,
AY033237,
AK300243,
BC064634,
AB075879,
AK056992
Ensembl:
ENSG00000147576
KO:
hsa:137872
|
| Nucleutide sequences |
EMBL-CDS:
BAB71335.1,
AAK44223.1,
BAD38661.1,
EAW86902.1,
EAW86903.1,
EAW86907.1,
AAH64634.1,
BAG62010.1
Gene_ORFName:
HMFT2263
Ensembl_TRS:
ENST00000396623,
ENST00000415254,
ENST00000424777
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000410883,
ENSP00000407115,
ENSP00000379865
RefSeq:
NP_653251.2
|
| Others |
UniRef100:
UniRef100_Q8IWW8
UniRef90:
UniRef90_Q8IWW8
UniRef50:
UniRef50_Q8IWW8
UniGene:
Hs.720023
CCDS:
CCDS6190.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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