| Type | Description |
|---|---|
| Definition | carnitine palmitoyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:25:00 | in 416 patients of acute encephalopathy, including both severe and mild syndrome, minor allele frequency of rs2229291 was significantly higher in acute encephalopathy with biphasic seizures (p=0.044), MERS (p=0.015) and entire acute encephalopathy (p=0.044) compared to the controls. | 31351739 |
| 2020-02-15 11:40:00 | rs1799822 in the CPT2 gene is associated with the severity of EV71 encephalitis in Chinese children. | 31201655 |
| 2019-12-21 10:17:00 | We used metabolomics to demonstrate that inhibition of CDK9 leads to accumulation of acyl-carnitines, metabolic intermediates in fatty acid oxidation (FAO). Acyl-carnitines are produced by carnitine palmitoyltransferase enzymes 1 and 2 (CPT), and we used both genetic and pharmacological tools to show that inhibition of CPT-activity is synthetically lethal with CDK9 inhibition | 31151054 |
| 2019-09-21 10:31:00 | Lack of activation of the S113L variant of carnitine palmitoyltransfersase II by cardiolipin. | 30604089 |
| 2019-03-30 12:43:00 | The results show that AMPK activation by GSK773 evokes the slow, oxidative myogenic program and triggers beneficial phenotypic adaptations in FAO-deficient myotubes. Thus, GSK773 might have therapeutic potential for correction of CPT2 deficiency | 30007356 |
| Type | IDs |
|---|---|
| Synonymous | CPT1, CPTASE, IIAE4 |
| Gene |
UniProtKB-ID:
CPT2_HUMAN,
A0A1B0GTB8_HUMAN,
A0A140VK13_HUMAN
UniprotKB:
P23786,
A0A1B0GTB8,
A0A140VK13
UniParc:
UPI000387DC1F,
UPI0000128303
EMBL:
AK312687,
U09645,
U09644,
HM005553,
BC002445,
BC005172,
U09646,
AL606760,
U09643,
U09648,
CH471059,
U09642,
M58581
Ensembl:
ENSG00000157184
KO:
hsa:1376
|
| Nucleutide sequences |
EMBL-CDS:
AAB60382.1,
AAB60383.1,
AAH05172.1,
BAG35567.1,
EAX06753.1,
AAH02445.1,
AAB59462.1,
AEE61150.1
Ensembl_TRS:
ENST00000371486,
ENST00000636867
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360541,
ENSP00000489631
RefSeq:
NP_001317518.1,
NP_000089.1
|
| Others |
UniRef100:
UniRef100_P23786,
UniRef100_A0A1B0GTB8
UniRef90:
UniRef90_P23786
UniRef50:
UniRef50_P23786
UniGene:
Hs.713535
CCDS:
CCDS575.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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