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1375 CPT1B

1375

CPT1B

carnitine palmitoyltransferase 1B

protein-coding

Homo sapiens

基因描述

Type Description
Definition carnitine palmitoyltransferase 1B

研究结论

Date Results Publications
2020-10-03 12:58:00 Targeting CPT1B as a potential therapeutic strategy in castration-resistant and enzalutamide-resistant prostate cancer. 32648618
2020-08-22 13:03:00 Low expression of CPT1B in high-grade urinary bladder cancer was associated with low fatty acid oxidation and low acyl carnitine levels. 30846479
2019-10-26 10:55:00 CPT1b overexpression could be helping to maintain metabolic health with increasing age. Thus, it is suggested that targeting CPT1b expression might be an interesting strategy to counteract frailty at an early stage. In addition, future studies should examine the role of sirtuin in CPT1b expression regulation. 29657112
2016-06-28 11:49:00 CPT1 is active on the outer surface of mitochondria and serves as a regulatory site for fatty acid oxidation due to its sensitivity for malonyl-CoA. CPT1b is the muscle isoform. 26041663
2016-03-05 11:04:00 In subjects with PTSD, significant over-expression of CPT1B was also observed in the two common dysregulated pathways: fatty acid metabolism and PPAR. 26080315

名称对应

Type IDs
Synonymous CPT1-M, CPT1M, CPTI, CPTI-M, M-CPT1, MCCPT1, MCPT1
Gene
UniProtKB-ID: CPT1B_HUMAN, A0A024R4W7_HUMAN, A5PLL0_HUMAN, Q53FV7_HUMAN
UniprotKB: Q92523, A0A024R4W7, A5PLL0, Q53FV7
UniParc: UPI000016144A, UPI000050A8D9, UPI0000128314, UPI000156571B, UPI000192C364, UPI0001914FC6
EMBL: BC142954, AB051457, AK223174, AB003286, Y08683, AK299395, U66828, U62733, AK297866, D87812, CH471138, U62317, Y08682
Ensembl: ENSG00000205560
KO: hsa:1375
Nucleutide sequences
EMBL-CDS: AAB40651.1, CAA69938.1, CAA69939.1, AAB03343.1, BAB33340.1, BAA21492.1, BAH13024.1, BAA13461.1, AAC51122.1, BAH12680.1, EAW73569.1, EAW73571.1, EAW73572.1, EAW73568.1, EAW73570.1, AAI42955.1, BAD96894.1
Gene_ORFName: hCG_2044796
Ensembl_TRS: ENST00000360719, ENST00000395650, ENST00000312108, ENST00000457250, ENST00000405237
Protein sequencees
Ensembl_PRO: ENSP00000312189, ENSP00000379011, ENSP00000409342, ENSP00000385486, ENSP00000353945
RefSeq: NP_001138607.1, NP_001138609.1, NP_689451.1, NP_004368.1, NP_001138606.1, NP_689452.1
Others
UniRef100: UniRef100_Q53FV7, UniRef100_Q92523, UniRef100_A5PLL0
UniRef90: UniRef90_Q92523
UniRef50: UniRef50_P32198
UniGene: Hs.439777, Hs.609867
CCDS: CCDS14098.1, CCDS46734.1

全选

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