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13711 Elf5

13711

Elf5

E74-like factor 5

protein-coding

Mus musculus

基因描述

Type Description
Definition E74-like factor 5

研究结论

Date Results Publications
2018-10-27 10:43:00 Downregulation of ELF5 increases the expression of AR-response genes and the progression of prostate cancer. ELF5 interaction with AR is androgen dependent. 28287091
2017-06-10 12:15:00 Conditional inactivation of Elf5 in the developing collecting ducts results in a small but significant reduction in the expression levels of Aqp2 and Avpr2 genes. 28215940
2017-01-14 10:52:00 Mechanistically, RL negatively regulates Stat5 phosphorylation and Elf5 expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin/p-Stat5 pathway. 26695351
2016-04-02 11:02:00 Elf5 at the center of a stoichiometry-sensitive transcriptional network, where it acts as a molecular switch governing the balance between TSC proliferation and differentiation 26584622
2015-02-14 10:10:00 Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner 25446535

名称对应

Type IDs
Synonymous ESE-2, ESE-5, ESE-5.
Gene
UniProtKB-ID: ELF5_MOUSE, Q3ULZ4_MOUSE, Q3V1F7_MOUSE
UniprotKB: Q8VDK3, Q3ULZ4, Q3V1F7
UniParc: UPI0000022B04, UPI00000E85B1
EMBL: AL954374, AL773505, AK132484, AK145214, AF049702, BC021629, BC012424
Ensembl: ENSMUSG00000027186
KO: mmu:13711
Nucleutide sequences
EMBL-CDS: AAH12424.1, AAC79754.1, AAH21629.1, BAE26304.1, BAE21194.1, CAM24572.1
Gene_ORFName: RP23-445A5.2-001
Ensembl_TRS: ENSMUST00000164172, ENSMUST00000028609, ENSMUST00000171693
Protein sequencees
Ensembl_PRO: ENSMUSP00000126941, ENSMUSP00000131940, ENSMUSP00000028609
RefSeq: NP_001139285.1, NP_034255.2, XP_006498768.1
Others
UniRef100: UniRef100_Q3ULZ4, UniRef100_Q8VDK3
UniRef90: UniRef90_D4A3N9, UniRef90_Q8VDK3
UniRef50: UniRef50_Q8VDK3, UniRef50_D4A3N9
UniGene: Mm.20888
CCDS: CCDS16477.1

全选

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