Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.

Cell Rep     Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.

Mol Cell Proteomics     Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck

Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

Binding of carboxypeptidase N to fibrinogen and fibrin.

Biochem. Biophys. Res. Commun.     S Talens , J H G Lebbink , J J M C Malfliet , J A A Demmers , S Uitte de Willige , F W G Leebeek , D C Rijken

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Nat. Genet.     Karol Estrada , Unnur Styrkarsdottir , Evangelos Evangelou , Yi-Hsiang Hsu , Emma L Duncan , Evangelia E Ntzani , Ling Oei , Omar M E Albagha , Najaf Amin , John P Kemp , Daniel L Koller , Guo Li , Ching-Ti Liu , Ryan L Minster , Alireza Moayyeri , Liesbeth Vandenput , Dana Willner , Su-Mei Xiao , Laura M Yerges-Armstrong , Hou-Feng Zheng , Nerea Alonso , Joel Eriksson , Candace M Kammerer , Stephen K Kaptoge , Paul J Leo , Gudmar Thorleifsson , Scott G Wilson , James F Wilson , Ville Aalto , Markku Alen , Aaron K Aragaki , Thor Aspelund , Jacqueline R Center , Zoe Dailiana , David J Duggan , Melissa Garcia , Natàlia Garcia-Giralt , Sylvie Giroux , Göran Hallmans , Lynne J Hocking , Lise Bjerre Husted , Karen A Jameson , Rita Khusainova , Ghi Su Kim , Charles Kooperberg , Theodora Koromila , Marcin Kruk , Marika Laaksonen , Andrea Z Lacroix , Seung Hun Lee , Ping C Leung , Joshua R Lewis , Laura Masi , Simona Mencej-Bedrac , Tuan V Nguyen , Xavier Nogues , Millan S Patel , Janez Prezelj , Lynda M Rose , Serena Scollen , Kristin Siggeirsdottir , Albert V Smith , Olle Svensson , Stella Trompet , Olivia Trummer , Natasja M van Schoor , Jean Woo , Kun Zhu , Susana Balcells , Maria Luisa Brandi , Brendan M Buckley , Sulin Cheng , Claus Christiansen , Cyrus Cooper , George Dedoussis , Ian Ford , Morten Frost , David Goltzman , Jesús González-Macías , Mika Kähönen , Magnus Karlsson , Elza Khusnutdinova , Jung-Min Koh , Panagoula Kollia , Bente Lomholt Langdahl , William D Leslie , Paul Lips , Östen Ljunggren , Roman S Lorenc , Janja Marc , Dan Mellström , Barbara Obermayer-Pietsch , José M Olmos , Ulrika Pettersson-Kymmer , David M Reid , José A Riancho , Paul M Ridker , François Rousseau , P Eline Slagboom , Nelson L S Tang , Roser Urreizti , Wim Van Hul , Jorma Viikari , María T Zarrabeitia , Yurii S Aulchenko , Martha Castano-Betancourt , Elin Grundberg , Lizbeth Herrera , Thorvaldur Ingvarsson , Hrefna Johannsdottir , Tony Kwan , Rui Li , Robert Luben , Carolina Medina-Gómez , Stefan Th Palsson , Sjur Reppe , Jerome I Rotter , Gunnar Sigurdsson , Joyce B J van Meurs , Dominique Verlaan , Frances M K Williams , Andrew R Wood , Yanhua Zhou , Kaare M Gautvik , Tomi Pastinen , Soumya Raychaudhuri , Jane A Cauley , Daniel I Chasman , Graeme R Clark , Steven R Cummings , Patrick Danoy , Elaine M Dennison , Richard Eastell , John A Eisman , Vilmundur Gudnason , Albert Hofman , Rebecca D Jackson , Graeme Jones , J Wouter Jukema , Kay-Tee Khaw , Terho Lehtimäki , Yongmei Liu , Mattias Lorentzon , Eugene McCloskey , Braxton D Mitchell , Kannabiran Nandakumar , Geoffrey C Nicholson , Ben A Oostra , Munro Peacock , Huibert A P Pols , Richard L Prince , Olli Raitakari , Ian R Reid , John Robbins , Philip N Sambrook , Pak Chung Sham , Alan R Shuldiner , Frances A Tylavsky , Cornelia M van Duijn , Nick J Wareham , L Adrienne Cupples , Michael J Econs , David M Evans , Tamara B Harris , Annie Wai Chee Kung , Bruce M Psaty , Jonathan Reeve , Timothy D Spector , Elizabeth A Streeten , M Carola Zillikens , Unnur Thorsteinsdottir , Claes Ohlsson , David Karasik , J Brent Richards , Matthew A Brown , Kari Stefansson , André G Uitterlinden , Stuart H Ralston , John P A Ioannidis , Douglas P Kiel , Fernando Rivadeneira

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

Nat Genet     John C Chambers , Weihua Zhang , Joban Sehmi , Xinzhong Li , Mark N Wass , Pim Van der Harst , Hilma Holm , Serena Sanna , Maryam Kavousi , Sebastian E Baumeister , Lachlan J Coin , Guohong Deng , Christian Gieger , Nancy L Heard-Costa , Jouke-Jan Hottenga , Brigitte Kühnel , Vinod Kumar , Vasiliki Lagou , Liming Liang , Jian'an Luan , Pedro Marques Vidal , Irene Mateo Leach , Paul F O'Reilly , John F Peden , Nilufer Rahmioglu , Pasi Soininen , Elizabeth K Speliotes , Xin Yuan , Gudmar Thorleifsson , Behrooz Z Alizadeh , Larry D Atwood , Ingrid B Borecki , Morris J Brown , Pimphen Charoen , Francesco Cucca , Debashish Das , Eco J C de Geus , Anna L Dixon , Angela Döring , Georg Ehret , Gudmundur I Eyjolfsson , Martin Farrall , Nita G Forouhi , Nele Friedrich , Wolfram Goessling , Daniel F Gudbjartsson , Tamara B Harris , Anna-Liisa Hartikainen , Simon Heath , Gideon M Hirschfield , Albert Hofman , Georg Homuth , Elina Hyppönen , Harry L A Janssen , Toby Johnson , Antti J Kangas , Ido P Kema , Jens P Kühn , Sandra Lai , Mark Lathrop , Markus M Lerch , Yun Li , T Jake Liang , Jing-Ping Lin , Ruth J F Loos , Nicholas G Martin , Miriam F Moffatt , Grant W Montgomery , Patricia B Munroe , Kiran Musunuru , Yusuke Nakamura , Christopher J O'Donnell , Isleifur Olafsson , Brenda W Penninx , Anneli Pouta , Bram P Prins , Inga Prokopenko , Ralf Puls , Aimo Ruokonen , Markku J Savolainen , David Schlessinger , Jeoffrey N L Schouten , Udo Seedorf , Srijita Sen-Chowdhry , Katherine A Siminovitch , Johannes H Smit , Timothy D Spector , Wenting Tan , Tanya M Teslovich , Taru Tukiainen , Andre G Uitterlinden , Melanie M Van der Klauw , Ramachandran S Vasan , Chris Wallace , Henri Wallaschofski , H-Erich Wichmann , Gonneke Willemsen , Peter Würtz , Chun Xu , Laura M Yerges-Armstrong , Alcohol Genome-wide Association (AlcGen) Consortium , Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study , Genetic Investigation of Anthropometric Traits (GIANT) Consortium , Global Lipids Genetics Consortium , Genetics of Liver Disease (GOLD) Consortium , International Consortium for Blood Pressure (ICBP-GWAS) , Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) , Goncalo R Abecasis , Kourosh R Ahmadi , Dorret I Boomsma , Mark Caulfield , William O Cookson , Cornelia M van Duijn , Philippe Froguel , Koichi Matsuda , Mark I McCarthy , Christa Meisinger , Vincent Mooser , Kirsi H Pietiläinen , Gunter Schumann , Harold Snieder , Michael J E Sternberg , Ronald P Stolk , Howard C Thomas , Unnur Thorsteinsdottir , Manuela Uda , Gérard Waeber , Nicholas J Wareham , Dawn M Waterworth , Hugh Watkins , John B Whitfield , Jacqueline C M Witteman , Bruce H R Wolffenbuttel , Caroline S Fox , Mika Ala-Korpela , Kari Stefansson , Peter Vollenweider , Henry Völzke , Eric E Schadt , James Scott , Marjo-Riitta Järvelin , Paul Elliott , Jaspal S Kooner

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.

Pharmacogenet. Genomics     Antonio Grilo , María P Sáez-Rosas , Juan Santos-Morano , Elena Sánchez , Concha Moreno-Rey , Luis M Real , Reposo Ramírez-Lorca , María E Sáez

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Nature     Hana Lango Allen , Karol Estrada , Guillaume Lettre , Sonja I Berndt , Michael N Weedon , Fernando Rivadeneira , Cristen J Willer , Anne U Jackson , Sailaja Vedantam , Soumya Raychaudhuri , Teresa Ferreira , Andrew R Wood , Robert J Weyant , Ayellet V Segrè , Elizabeth K Speliotes , Eleanor Wheeler , Nicole Soranzo , Ju-Hyun Park , Jian Yang , Daniel Gudbjartsson , Nancy L Heard-Costa , Joshua C Randall , Lu Qi , Albert Vernon Smith , Reedik Mägi , Tomi Pastinen , Liming Liang , Iris M Heid , Jian'an Luan , Gudmar Thorleifsson , Thomas W Winkler , Michael E Goddard , Ken Sin Lo , Cameron Palmer , Tsegaselassie Workalemahu , Yurii S Aulchenko , Asa Johansson , M Carola Zillikens , Mary F Feitosa , Tõnu Esko , Toby Johnson , Shamika Ketkar , Peter Kraft , Massimo Mangino , Inga Prokopenko , Devin Absher , Eva Albrecht , Florian Ernst , Nicole L Glazer , Caroline Hayward , Jouke-Jan Hottenga , Kevin B Jacobs , Joshua W Knowles , Zoltán Kutalik , Keri L Monda , Ozren Polasek , Michael Preuss , Nigel W Rayner , Neil R Robertson , Valgerdur Steinthorsdottir , Jonathan P Tyrer , Benjamin F Voight , Fredrik Wiklund , Jianfeng Xu , Jing Hua Zhao , Dale R Nyholt , Niina Pellikka , Markus Perola , John R B Perry , Ida Surakka , Mari-Liis Tammesoo , Elizabeth L Altmaier , Najaf Amin , Thor Aspelund , Tushar Bhangale , Gabrielle Boucher , Daniel I Chasman , Constance Chen , Lachlan Coin , Matthew N Cooper , Anna L Dixon , Quince Gibson , Elin Grundberg , Ke Hao , M Juhani Junttila , Lee M Kaplan , Johannes Kettunen , Inke R König , Tony Kwan , Robert W Lawrence , Douglas F Levinson , Mattias Lorentzon , Barbara McKnight , Andrew P Morris , Martina Müller , Julius Suh Ngwa , Shaun Purcell , Suzanne Rafelt , Rany M Salem , Erika Salvi , Serena Sanna , Jianxin Shi , Ulla Sovio , John R Thompson , Michael C Turchin , Liesbeth Vandenput , Dominique J Verlaan , Veronique Vitart , Charles C White , Andreas Ziegler , Peter Almgren , Anthony J Balmforth , Harry Campbell , 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Christian Gieger , Henrik Grönberg , Per Hall , Andrew T Hattersley , Christian Hengstenberg , Wolfgang Hoffman , G Mark Lathrop , Veikko Salomaa , Stefan Schreiber , Manuela Uda , Dawn Waterworth , Alan F Wright , Themistocles L Assimes , Inês Barroso , Albert Hofman , Karen L Mohlke , Dorret I Boomsma , Mark J Caulfield , L Adrienne Cupples , Jeanette Erdmann , Caroline S Fox , Vilmundur Gudnason , Ulf Gyllensten , Tamara B Harris , Richard B Hayes , Marjo-Riitta Jarvelin , Vincent Mooser , Patricia B Munroe , Willem H Ouwehand , Brenda W Penninx , Peter P Pramstaller , Thomas Quertermous , Igor Rudan , Nilesh J Samani , Timothy D Spector , Henry Völzke , Hugh Watkins , James F Wilson , Leif C Groop , Talin Haritunians , Frank B Hu , Robert C Kaplan , Andres Metspalu , Kari E North , David Schlessinger , Nicholas J Wareham , David J Hunter , Jeffrey R O'Connell , David P Strachan , H-Erich Wichmann , Ingrid B Borecki , Cornelia M van Duijn , Eric E Schadt , Unnur Thorsteinsdottir , Leena Peltonen , André G Uitterlinden , Peter M Visscher , Nilanjan Chatterjee , Ruth J F Loos , Michael Boehnke , Mark I McCarthy , Erik Ingelsson , Cecilia M Lindgren , Gonçalo R Abecasis , Kari Stefansson , Timothy M Frayling , Joel N Hirschhorn

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.

Hepatology     Elizabeth K Speliotes , Johannah L Butler , Cameron D Palmer , Benjamin F Voight , GIANT Consortium , MIGen Consortium , NASH CRN , Joel N Hirschhorn