| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4E binding protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:54:00 | Diabetes enhances translation of Cd40 mRNA in murine retinal Muller glia via a 4E-BP1/2-dependent mechanism. | 32475820 |
| 2020-09-26 13:06:00 | Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-kappaB Activity. | 31825840 |
| 2020-06-27 12:26:00 | 4E-BP1 and 4E-BP2 contributes to the maintenance of muscle mass and function in aging through increased protein synthesis. Through metabolomic and global lipid analysis, study demonstrated that 4E-BPs play a role in the control of energy and amino acid metabolism in the skeletal muscle of 24-month-old mice. Thus, 4E-BPs may be potential drug targets in the treatment of sarcopenia. | 30927336 |
| 2020-03-28 10:26:00 | evidence for an inhibitory-cell-specific role of 4E-BP2 in engendering autism-related behaviors. | 31427534 |
| 2019-04-13 12:04:00 | Genetic deletion of 4E-BP1/2 in macrophages increased endogenous IL-10. | 29712774 |
| Type | IDs |
|---|---|
| Synonymous | 2810011I19Rik, 4E-BP2, AA792569, BC010348, PHAS-II |
| Gene |
UniProtKB-ID:
4EBP2_MOUSE,
Q3UFP6_MOUSE
UniprotKB:
P70445,
Q3UFP6
UniParc:
UPI0000021810
EMBL:
AK148374,
BC119539,
U75530,
BC015082
Ensembl:
ENSMUSG00000020091
KO:
mmu:13688
|
| Nucleutide sequences |
EMBL-CDS:
AAH15082.1,
AAC52899.1,
AAI19540.1,
BAE28514.1
Ensembl_TRS:
ENSMUST00000020288,
ENSMUST00000167087
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131952,
ENSMUSP00000020288
RefSeq:
NP_034254.1
|
| Others |
UniRef100:
UniRef100_P70445
UniRef90:
UniRef90_P70445
UniRef50:
UniRef50_P70445
UniGene:
Mm.259516
CCDS:
CCDS23879.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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