| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4E |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:35:00 | The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity. | 33619378 |
| 2020-04-11 11:48:00 | Phosphorylation of eIF4E at Ser209 is dispensable for skeletal muscle hypertrophy in response to mechanical overload. | 31596607 |
| 2020-03-21 11:21:00 | phosphorylation pattern of eIF4E responds faithfully to Rapamycin inhibition, the prolonged exposure to Rapamycin rescues the loss of eIF4E phosphorylation through Mnk1 activation. | 31782083 |
| 2019-10-19 12:12:00 | 4E-BP/eIF4E can regulate expression of important proteins necessary for B cell differentiation. Rap reduces eIF4E and eIF4G association to inhibit cap-dependent translation in activated B cells and that directly inhibiting eIF4E activity can also reduce antibody class switching. | 30530594 |
| 2019-05-25 10:07:00 | We reveal a novel role for eIF4E phosphorylation in inflammatory responses and depression-like behaviors | 29367404 |
| Type | IDs |
|---|---|
| Synonymous | EG668879, Eif4e-ps, If4e, eIF-4E |
| Gene |
UniProtKB-ID:
IF4E_MOUSE,
Q8C470_MOUSE,
A0A0G2JFB4_MOUSE,
Q3TK95_MOUSE
UniprotKB:
P63073,
Q8C470,
A0A0G2JFB4,
Q3TK95
UniParc:
UPI00006047FC,
UPI00000018EA,
UPI00000E9E2F
EMBL:
BC085087,
AC113988,
M61731,
AK082867,
AK167097,
BC010759
Ensembl:
ENSMUSG00000028156
KO:
mmu:13684
|
| Nucleutide sequences |
EMBL-CDS:
AAA37545.1,
AAH10759.1,
AAH85087.1,
BAC38660.1,
BAE39250.1
Ensembl_TRS:
ENSMUST00000029803,
ENSMUST00000196990
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029803,
ENSMUSP00000143104
RefSeq:
NP_031943.3,
XP_017174942.1,
XP_036018780.1,
XP_006501056.1,
NP_001300909.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JFB4,
UniRef100_Q8C470,
UniRef100_P63073
UniRef90:
UniRef90_A0A0G2JFB4,
UniRef90_P63073,
UniRef90_P29338
UniRef50:
UniRef50_P06730,
UniRef50_P63073
UniGene:
Mm.3941,
Mm.488704
CCDS:
CCDS38654.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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