| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4A1 |
| Date | Results | Publications |
|---|---|---|
| 2011-12-24 10:04:00 | the central A-rich domains of BC RNAs target eIF4A, specifically inhibiting its RNA helicase activity | 21930783 |
| 2011-07-16 11:30:00 | analysis of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G | 21454508 |
| 2010-01-21 00:00:00 | Pdcd4 binding to eIF4A is linked to its transformation-suppressing activity, as Pdcd4-eIF4A binding and consequent inhibition of translation are required for Pdcd4 transrepression of AP-1. | 12482958 |
| 2010-01-21 00:00:00 | interactions between Pdcd4 and components of the translation initiation complex, namely, the RNA helicase eIF4A and the scaffolding protein eIF4G | 17060447 |
| 2010-01-21 00:00:00 | The binding of pateamine to eIF4A presets the protein in the high-affinity RNA-binding state, which stimulates ATP binding, hydrolysis, and RNA unwinding. | 16030146 |
| Type | IDs |
|---|---|
| Synonymous | BM-010, Ddx2a, Eif4 |
| Gene |
UniProtKB-ID:
IF4A1_MOUSE,
Q3TLL6_MOUSE,
Q5F2A7_MOUSE
UniprotKB:
P60843,
Q3TLL6,
Q5F2A7
UniParc:
UPI000000411B,
UPI00005B226B
EMBL:
AK167196,
L36608,
L36610,
AK145508,
AK166527,
AK167003,
AK145375,
AK077429,
AK135994,
AK169023,
L36611,
AK167988,
L36609,
AK152694,
AK167083,
AK169279,
AB011595,
BC049915,
AK146424,
AK166674,
AK166439,
AK167205,
AK169030,
AK159643,
X03039,
AK169057,
M22873,
AK166572,
AK144850,
AK146464,
AK168780,
X03040
Ensembl:
ENSMUSG00000059796
KO:
mmu:13681
|
| Nucleutide sequences |
EMBL-CDS:
BAA25075.1,
CAA26843.1,
CAA26842.1,
CAA26846.1,
BAC36796.1,
AAH49915.1,
AAA50407.1,
CAA26845.1,
BAE38776.1,
BAE22765.1,
BAE40845.1,
BAE39979.1,
BAE41037.1,
BAE26397.1,
BAE38831.1,
BAE26099.1,
BAE40821.1,
BAE26477.1,
BAE39332.1,
BAE27191.1,
BAE39326.1,
BAE40614.1,
BAE31424.1,
BAE35256.1,
BAE39241.1,
BAE38862.1,
BAE39182.1,
BAE38935.1,
BAE40818.1,
BAE27158.1
Ensembl_TRS:
ENSMUST00000163666
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000127034
RefSeq:
NP_659207.1,
NP_001152847.1
|
| Others |
UniRef100:
UniRef100_Q3TLL6,
UniRef100_P60842
UniRef90:
UniRef90_J3KT12,
UniRef90_P60842
UniRef50:
UniRef50_P60842,
UniRef50_A0A674HTV7
UniGene:
Mm.279821,
Mm.371557,
Mm.473799
CCDS:
CCDS24904.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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