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13660 Ehd1

13660

Ehd1

EH-domain containing 1

protein-coding

Mus musculus

基因描述

Type Description
Definition EH-domain containing 1

研究结论

Date Results Publications
2020-12-12 13:24:00 Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery. 32041776
2019-10-26 11:31:00 We edited the Ehd1 gene in cell lines as well as mice using CRISPR/Cas9, and found that the genotype distribution was significantly different. The lethal allele index calculated from these data was similar to the value calculated from the International Mouse Phenotyping Consortium data 30375401
2018-08-04 10:08:00 EHD1, EHD2, and EHD4 are recruited to caveolae. Recruitment of the other EHDs increases markedly when EHD2, which has been previously detected at caveolae, is absent. Construction of knockout cell lines lacking EHDs 1, 2, and 4 confirms this apparent functional redundancy. 28943089
2017-12-02 12:12:00 These findings reveal a novel and functionally important role for EHD1 in governing CSF-1R signalling via regulation of anterograde transport of CSF-1R to the macrophage cell surface. 27224507
2016-06-04 10:24:00 regulates the maintenance of T-tubules through its interaction with BIN1 26325203

名称对应

Type IDs
Synonymous AA409636, Past1, RME-1
Gene
UniProtKB-ID: EHD1_MOUSE, Q80ZZ0_MOUSE
UniprotKB: Q9WVK4, Q80ZZ0
UniParc: UPI00000041C3
EMBL: AK159943, AF173156, BC054828, AK166701, AK154651, AK088980, AK172539, BC043332, AK012896, AF099186
Ensembl: ENSMUSG00000024772, ENSMUSG00000107039
KO: mmu:13660
Nucleutide sequences
EMBL-CDS: AAF24223.1, BAB28540.1, AAD45423.1, BAE38956.1, AAH43332.2, BAE35499.1, BAE43057.1, BAE32742.1, BAC40684.1, AAH54828.2
Ensembl_TRS: ENSMUST00000202020, ENSMUST00000025684
Protein sequencees
Ensembl_PRO: ENSMUSP00000025684, ENSMUSP00000144036
RefSeq: NP_034249.1
Others
UniRef100: UniRef100_Q9WVK4
UniRef90: UniRef90_Q9H4M9
UniRef50: UniRef50_Q9NZN3
UniGene: Mm.30169
CCDS: CCDS29501.1

全选

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研究热度

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