Type | Description |
---|---|
Definition | early growth response 4 |
Date | Results | Publications |
---|---|---|
2011-12-10 10:51:00 | Egr4 expression is triggered by trophic factor neurturin to upregulate K-Cl cotransporter KCC2 in immature neurons. | 21837281 |
2011-02-26 11:19:00 | Egr4 is an important component in the mechanism of BDNF-dependent KCC2 gene regulation via the ERK1/2 pathway in immature neurons. | 21228173 |
2011-02-05 11:00:00 | Data suggest that Egr4 may regulate spermatogenesis at multiple steps, with roles in the dividing Sertoli cells, peritubular myoid cells, and the meiotic and elongating haploid germ cell populations. | 20925118 |
2010-01-21 00:00:00 | An important role for Egr4 is indicated in the developmental upregulation of potassium-chloride cotransporter (KCC2) gene expression. | 17192429 |
Type | IDs |
---|---|
Synonymous | NGF1-C, NGFI-C, NGFIC, pAT133 |
Gene |
UniProtKB-ID:
EGR4_MOUSE,
Q3URA9_MOUSE
UniprotKB:
Q9WUF2,
Q3URA9
UniParc:
UPI0000025FF8
EMBL:
AF132613,
AK141637
Ensembl:
ENSMUSG00000071341
KO:
mmu:13656
|
Nucleutide sequences |
EMBL-CDS:
AAD28267.1,
BAE24779.1
Ensembl_TRS:
ENSMUST00000095759
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000093433
RefSeq:
NP_065621.1
|
Others |
UniRef100:
UniRef100_Q9WUF2
UniRef90:
UniRef90_Q00911
UniRef50:
UniRef50_Q00911
UniGene:
Mm.44137
CCDS:
CCDS20297.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
21228173 |
Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription. J. Neurosci. Anastasia Ludwig , Pavel Uvarov , Shetal Soni , Judith Thomas-Crusells , Matti S Airaksinen , Claudio Rivera |
2011-01-12 | - |
21837281 |
Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons. Neural Plast. Anastasia Ludwig , Pavel Uvarov , Christophe Pellegrino , Judith Thomas-Crusells , Sebastian Schuchmann , Mart Saarma , Matti S Airaksinen , Claudio Rivera |
2011-01-01 |
Egr4,
Slc12a5
|
20925118 |
Dev Dyn Cathryn A Hogarth , Debra Mitchell , Christopher Small , Michael Griswold |
2010-11-01 | - |
20059953 |
Dev Cell Shigetoshi Yokoyama , Yoshiaki Ito , Hiroe Ueno-Kudoh , Hirohito Shimizu , Kenta Uchibe , Sonia Albini , Kazuhiko Mitsuoka , Shigeru Miyaki , Minako Kiso , Akane Nagai , Tomohiro Hikata , Tadahiro Osada , Noritsugu Fukuda , Satoshi Yamashita , Daisuke Harada , Valeria Mezzano , Masataka Kasai , Pier Lorenzo Puri , Yoshihide Hayashizaki , Haruo Okado , Megumi Hashimoto , Hiroshi Asahara |
2009-12-01 | - |
19741146 |
J. Neurosci. Hui Fu , Jun Cai , Hans Clevers , Eva Fast , Susan Gray , Rachel Greenberg , Mukesh K Jain , Qiufu Ma , Mengsheng Qiu , David H Rowitch , Christopher M Taylor , Charles D Stiles |
2009-09-09 |
Arntl,
Atf4,
Neurod4,
Ctnnb1,
Cnp,
Atf6b,
Csrp2,
E2f1,
E2f3,
E2f5,
Egr4,
Erf,
Foxm1,
Gfap,
Glul,
Gtf2i,
Hes5,
Foxj1,
Hmgb1,
Hmg20b,
Hoxd3,
Id1,
Id2,
Id3,
Irx1,
Irx3,
Lhx2,
Lhx4,
Lhx8,
Mxd3,
Mbp,
Mid1,
Mki67,
Foxk1,
Nfatc3,
Nfia,
Nfib,
Nfix,
Nkx2-2,
Nkx6-1,
Nsd1,
Otx2,
Pax3,
Pax7,
Pdgfra,
Per2,
Pknox1,
Plp1,
Phf21a,
Rest,
Rfx3,
Rxra,
Rxrb,
Six5,
Smarcc1,
Sox10,
Sox14,
Sox2,
Sox9,
Sp1,
Srebf1,
Tcf12,
Tcf4,
Tcf7l1,
Tcf7l2,
Tcf3,
Tfeb,
Tead2,
Tfdp1,
Btf3,
Nr2e1,
Trp53,
Nr1h2,
Sox21,
Zfp26,
Tgif2,
Tbpl1,
E2f2,
Ciao1,
Brd7,
Pdlim4,
E2f6,
Sall2,
Olig2,
Olig1,
Foxo4,
Prickle3,
Cited4,
Smarce1,
Klf15,
Bbx,
Rfx4,
Zkscan3,
Tsc22d4,
Hmgb2
|
18287559 |
GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project |
2008-04-01 | - |
17192429 |
J. Neurosci. Pavel Uvarov , Anastasia Ludwig , Marika Markkanen , Claudio Rivera , Matti S Airaksinen |
2006-12-27 | - |
16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
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