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13641 Efnb1

13641

Efnb1

ephrin B1

protein-coding

Mus musculus

基因描述

Type Description
Definition ephrin B1

研究结论

Date Results Publications
2021-01-02 12:52:00 Astrocytic Ephrin-B1 Controls Excitatory-Inhibitory Balance in Developing Hippocampus. 32801156
2020-05-16 11:44:00 Using mice harboring mutations in the Efnb1 and in Ephb1-3 receptor genes in different embryonic tissues study established the tissue-specific contributions of EPHRIN-B1 mosaicism to craniofacial dysmorphology and revealed specific cellular context and signaling interactions that are likely to underlie craniofrontonasal syndrome providing new understanding of how EPHRIN-B1 may regulate normal craniofacial development. 32092051
2019-12-21 11:23:00 EphrinB1, expressed by osteoprogenitors, influences bone loss during the development of osteoporosis, by regulating both osteoblast and osteoclast formation and function, leading to a loss of skeletal integrity. 30143786
2019-10-19 11:01:00 Our findings demonstrate that astrocytic ephrin-B1 regulates long-term contextual memory by restricting new synapse formation in the adult hippocampus 29793972
2019-10-12 10:37:00 Post-crossing CCAs switch off their response to axon guidance cues, among which the secreted Semaphorin-3C (Sema3C), that act as attractants for pre-crossing axons on their way to the midline. This change is concomitant with an upregulation of the surface protein Ephrin-B1, which acts in CCAs to inhibit Sema3C signaling via interaction with the Neuropilin-1 (Nrp1) receptor. 29779877

名称对应

Type IDs
Synonymous Cek5-L, EFL-3, Elk-L, Epl2, Eplg2, LERK-2, Lerk2, Stra1
Gene
UniProtKB-ID: EFNB1_MOUSE, Q544L9_MOUSE
UniprotKB: P52795, Q544L9
UniParc: UPI00000018AC
EMBL: AK034996, U07599, U07600, BC006797, U12983, BC021656, Z48781, U07602, U07598
Ensembl: ENSMUSG00000031217
KO: mmu:13641
Nucleutide sequences
EMBL-CDS: AAA53231.1, AAH21656.1, CAA88695.1, AAH06797.1, AAC53247.1, BAC28907.1
Ensembl_TRS: ENSMUST00000052839
Protein sequencees
Ensembl_PRO: ENSMUSP00000050716
RefSeq: NP_034240.1
Others
UniRef100: UniRef100_P52795
UniRef90: UniRef90_P52795
UniRef50: UniRef50_P52795
UniGene: Mm.3374
CCDS: CCDS30298.1

全选

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