| Type | Description |
|---|---|
| Definition | ephrin A2 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 14:13:00 | The loss of Ephrin-A2 and A5 ligands did not impact on the rate of wound closure or re-innervation after injury. However, changes in the gross morphology of the healed scar and in collagen histology of the scar dermis were observed in transgenic mice. Therefore Ephrin-A2 and A5 ligands may play an important role in final scar appearance associated with collagen deposition and structure. | 30482614 |
| 2019-06-29 11:07:00 | ephrin-A2 participates in the creation of excitatory neurons by inhibiting apical progenitor proliferation in the ventricular zone, with the disruption of ephrin-A2 signaling in these cells recapitulating the abnormal neocortex observed in the knockout. | 28924206 |
| 2019-01-12 11:48:00 | Study showed that in comparison with wild-type mice revealed that ephrin-A2A5-/- mice had reduced accuracy and response rates, suggesting a goal-directed behavioral deficit, which was improved by low intensity repetitive transcranial magnetic stimulation. | 29464193 |
| 2015-12-19 10:11:00 | The ephrin-A2/-A3 DKO mice have utility as a novel ASD model with an emphasis on sensory abnormalities and restricted, repetitive behavioral symptoms. | 25281279 |
| 2015-07-25 11:30:00 | The results of this study suggested that majority of the changes observed ephrin-A2 and ephrin-A5 KO mice appear to be mediated by the effects on motor neurons and their muscle targets, rather than changes in auditory sensitivity. | 25200515 |
| Type | IDs |
|---|---|
| Synonymous | CEK7L, Elf1, Epl6, Eplg6, Lerk6 |
| Gene |
UniProtKB-ID:
EFNA2_MOUSE,
Q3USB4_MOUSE
UniprotKB:
P52801,
Q3USB4
UniParc:
UPI0000020CE3,
UPI00005ABFD1
EMBL:
AK140544,
U14752,
BC048697,
U14941
Ensembl:
ENSMUSG00000003070
KO:
mmu:13637
|
| Nucleutide sequences |
EMBL-CDS:
AAH48697.1,
AAA68520.1,
AAA53636.1,
BAE24419.1
Ensembl_TRS:
ENSMUST00000003154
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003154
RefSeq:
NP_031935.3
|
| Others |
UniRef100:
UniRef100_P52801,
UniRef100_Q3USB4
UniRef90:
UniRef90_Q3USB4,
UniRef90_P52801
UniRef50:
UniRef50_O43921,
UniRef50_P52801
UniGene:
Mm.1478
CCDS:
CCDS24013.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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