| Type | Description |
|---|---|
| Definition | embryonic ectoderm development |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 12:23:00 | these findings established a critical role of EED in the development of hippocampal dentate gyrus, which might shed new light on the molecular mechanism of intellectual disability in patients with EED mutations. | 31204298 |
| 2020-03-21 10:53:00 | In maternal-null (Eed(m-/-)) but not zygotic-null (Eed(-/-)) early embryos, the maternal X-chromosome ectopically induced Xist and underwent inactivation. Expression of PRC2 in the oocyte and transmission of the gene products to the embryo may dictate the occurrence of imprinted X-inactivation in mammals. | 30938678 |
| 2019-09-21 11:32:00 | These findings identify Eed/PRC2 as necessary for maintenance of global gene silencing and terminal differentiation in b cells, and suggest a ''two-hit'' (chromatin and hyperglycemia) model of b cell dedifferentiation. | 29754954 |
| 2019-06-29 11:04:00 | These data reveal a novel epigenetic regulated pathway and suggest an essential role for Eed in SVZ homeostasis and injury. | 29415247 |
| 2019-04-13 11:29:00 | Eed, an essential component of the Polycomb group complex 2 (PRC2), is required for establishing H3K27me3 imprinting | 30463900 |
| Type | IDs |
|---|---|
| Synonymous | l(7)5Rn, l7Rn5, lusk |
| Gene |
UniProtKB-ID:
EED_MOUSE
UniprotKB:
Q921E6
UniParc:
UPI00000622EF,
UPI000178DE51,
UPI00000E88CF
EMBL:
U78103,
BC012966,
AK077664,
AK133890,
U97675,
AK131976
Ensembl:
ENSMUSG00000030619
KO:
mmu:13626
|
| Nucleutide sequences |
EMBL-CDS:
BAC36938.1,
AAB38319.1,
AAC53302.1,
AAH12966.1,
BAE20916.1,
BAE21915.1
Ensembl_TRS:
ENSMUST00000107234,
ENSMUST00000238981
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000159149,
ENSMUSP00000102853
RefSeq:
NP_068676.1
|
| Others |
UniRef100:
UniRef100_O75530
UniRef90:
UniRef90_O75530
UniRef50:
UniRef50_O75530
UniGene:
Mm.380914
CCDS:
CCDS40016.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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