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136259 KLF14

136259

KLF14

Kruppel like factor 14

protein-coding

Homo sapiens

基因描述

Type Description
Definition Kruppel like factor 14

研究结论

Date Results Publications
2021-01-09 13:32:00 Epstein-Barr Virus Facilitates Expression of KLF14 by Regulating the Cooperative Binding of the E2F-Rb-HDAC Complex in Latent Infection. 32847849
2020-03-07 12:43:00 These results provide comprehensive insight into the KLF14-dependent regulation of antioxidant response and subsequent pathogenesis of castration resistance and indicate that interventions targeting the KLF14/HO-1 adaptive mechanism should be further explored for castration-resistant prostate cancer treatment. 30400002
2019-11-23 10:07:00 KLF14 inhibits the inflammatory response in endothelial cells; its protective effects are mediated by transcriptional inhibition of NF-kappaB p65 30248551
2019-10-05 11:50:00 we proved that DGCR5 can rescue the inhibited levels of KLF14 repressed by miR-346 mimics in MHCC-97H and Hep3B cells. Taken together, it was indicated in our study that DGCR5 can restrain the progression of HCC through sponging miR-346 and modulating KLF14 in vitro. 30216442
2019-09-14 10:14:00 The modified methylation of TRIM59 and KLF14 in top athletes may be accounted for by the biological roles played by these genes. Their known anti-tumour and anti-inflammatory activities suggests that intense physical training has a complex influence on aging and potentially launches signalling networks that contribute to the observed lower risk of elite athletes to develop cardiovascular disease and cancer. 29466246

名称对应

Type IDs
Synonymous BTEB5
Gene
UniProtKB-ID: KLF14_HUMAN
UniprotKB: Q8TD94
UniParc: UPI000274712B
EMBL: CH471070, CH236950, DQ534757, DQ534756, AF490374, AC234644
Ensembl: ENSG00000266265
KO: hsa:136259
Nucleutide sequences
EMBL-CDS: EAL24083.1, EAW83773.1, ABF82393.1, ABF82392.1, AAM08349.1
Ensembl_TRS: ENST00000583337
Protein sequencees
Ensembl_PRO: ENSP00000463287
RefSeq: NP_619638.2
Others
UniRef100: UniRef100_Q8TD94
UniRef90: UniRef90_Q8TD94
UniRef50: UniRef50_Q8TD94
UniGene: Hs.125240
CCDS: CCDS5825.1

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