| Type | Description |
|---|---|
| Definition | carboxypeptidase D |
| Date | Results | Publications |
|---|---|---|
| 2018-03-17 11:20:00 | prolactin induction of VEGF-C and Runx2 was inhibited partly by Carboxypeptidase-D inhibitors, implicating nitric oxide , produced by PRL-regulated Carboxypeptidase-D, in breast cancer progression | 28364216 |
| 2017-02-18 12:28:00 | Carboxypeptidase-D (CPD) overexpression coincides with high-grade lung cancer and the CPD overexpression could reverse the inhibitory effects of miR-214 | 27494742 |
| 2015-03-07 12:20:00 | The human carboxypeptidase D transthyretin-like domain forms amyloid under physiological conditions. | 25294878 |
| 2014-11-08 11:15:00 | Prolactin and R1881, acting through Stat5 and androgen receptor, act cooperatively to stimulate CPD gene transcription in breast cancer cells. | 24433040 |
| 2014-06-14 13:17:00 | CPD immunostaining and testosterone/prolactin-stimulated CPD expression were higher in prostate cancer than benign tissues/cells. Elevated CPD increased NO production, which was abolished when both androgen and prolactin receptors were inhibited. | 24615730 |
| Type | IDs |
|---|---|
| Synonymous | GP180 |
| Gene |
UniProtKB-ID:
CBPD_HUMAN
UniprotKB:
O75976
UniParc:
UPI000000DAF7,
UPI0001ED0510
EMBL:
BC045549,
U65090,
AC006050,
AK316409,
BC045624,
BC051702,
D85390,
AK302497,
AC090685
Ensembl:
ENSG00000108582
KO:
hsa:1362
|
| Nucleutide sequences |
EMBL-CDS:
AAC51775.2,
AAH45549.1,
BAH14780.1,
AAH45624.1,
BAA33370.1,
AAH51702.1,
BAH13725.1
Ensembl_TRS:
ENST00000225719,
ENST00000543464
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000225719,
ENSP00000444443
RefSeq:
NP_001186704.1,
NP_001295.2
|
| Others |
UniRef100:
UniRef100_O75976
UniRef90:
UniRef90_O75976
UniRef50:
UniRef50_Q9JHW1
UniGene:
Hs.446079
CCDS:
CCDS56025.1,
CCDS11257.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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