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13617 Ednra

13617

Ednra

endothelin receptor type A

protein-coding

Mus musculus

基因描述

Type Description
Definition endothelin receptor type A

研究结论

Date Results Publications
2021-01-16 15:57:00 Loss-of-function of Endothelin receptor type A results in Oro-Oto-Cardiac syndrome. 32133772
2020-10-24 14:06:00 Endothelin receptor-A mediates degradation of the glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells. 31402170
2020-05-30 10:57:00 TRPA1 acts as a molecular target for ET-1, and sensitization of TRPA1 through pathway contributes to ET-1-induced mechanical hyperalgesia. 30990108
2020-04-18 11:19:00 The same anatomical and physiological consequences occur in Ednra(+/-); Plxna4(+/-) double heterozygotes, genetically confirming functional interaction. Second-order axon guidance therefore multiplexes a smaller number of guidance cues in sequential fashion, allowing precise refinement of axon trajectories. 30735130
2019-08-03 12:10:00 Our findings suggest that endothelin type A receptor is a potential target for the management of sickle cell disease-associated pain, although this expectation needs to be further verified in clinical settings. 29545351

名称对应

Type IDs
Synonymous AEA001, ET-AR, ETa, Gpcr10, Mhdaaea1
Gene
UniProtKB-ID: EDNRA_MOUSE
UniprotKB: Q61614
UniParc: UPI000002926E
EMBL: AK043210, L20340, AF039892, BC008277
Ensembl: ENSMUSG00000031616
KO: mmu:13617
Nucleutide sequences
EMBL-CDS: AAA16845.1, BAC31493.1, AAH08277.1, AAB96671.1
Ensembl_TRS: ENSMUST00000034029
Protein sequencees
Ensembl_PRO: ENSMUSP00000034029
RefSeq: NP_034462.1
Others
UniRef100: UniRef100_Q61614
UniRef90: UniRef90_P26684
UniRef50: UniRef50_P26684
UniGene: Mm.283168, Mm.392296
CCDS: CCDS22427.1

全选

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研究热度

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