| Type | Description |
|---|---|
| Definition | ectodysplasin-A receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 13:21:00 | Author report an unexpected pro-apoptotic activity of EDAR when unbound to its ligand Eda-A1, which is independent of NF-kappaB pathway. Contrarily to other death receptors, EDAR does recruit caspase-8 to trigger apoptosis but solely upon ligand withdrawal, thereby behaving as the so-called dependence receptors. | 29855541 |
| 2019-11-09 11:37:00 | broad activation of Edar expression precedes its spatial restriction to tooth signaling centers. | 30730874 |
| 2017-09-16 12:23:00 | EDAR protein signaling pathway plays an important role in wound healing in mice and human. | 26829034 |
| 2017-07-15 10:33:00 | Mouse models with HED also carry Eda, Edar or Edaradd mutations and have defects that map to the same structures.We report that otitis media, rhinitis and nasopharyngitis occur at high frequency in Eda and Edar mutant mice and explore the pathogenic mechanisms related to glandular function, microbial and immune parameters in these lines | 27378689 |
| 2016-04-09 10:33:00 | Edar is expressed in the developing ear. Edar-deficient mice have an abnormally shaped pinna. | 26105758 |
| Type | IDs |
|---|---|
| Synonymous | ED1R, ED3, ED5, EDA-A1R, EDA3, dl |
| Gene |
UniProtKB-ID:
EDAR_MOUSE
UniprotKB:
Q9R187
UniParc:
UPI0000020CFD
EMBL:
AK004576,
AF160502
Ensembl:
ENSMUSG00000003227
KO:
mmu:13608
|
| Nucleutide sequences |
EMBL-CDS:
AAD50425.1,
BAB23385.1
Ensembl_TRS:
ENSMUST00000003312
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003312
RefSeq:
XP_030100729.1,
NP_034230.1,
XP_006513268.1,
XP_006513267.1,
XP_006513269.1
|
| Others |
UniRef100:
UniRef100_Q9R187
UniRef90:
UniRef90_Q9R187
UniRef50:
UniRef50_Q9UNE0
UniGene:
Mm.174523
CCDS:
CCDS23862.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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