| Type | Description |
|---|---|
| Definition | extracellular matrix protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:31:00 | Studied the role of extracellular matrix protein 1 (ECM1) in controlling colonic inflammation through macrophages in inflammatory bowel disease (IBD). Findings show that ECM1 has an important function in promoting M1 macrophage polarization. | 31980528 |
| 2019-12-21 10:35:00 | ECM1, produced by hepatocytes, inhibits activation of TGFB and its activation of hepatic stellate cells to prevent fibrogenesis in mouse liver. | 31362006 |
| 2019-11-16 12:42:00 | findings suggest ECM1 is released from infiltrating inflammatory cells, which leads to cardiac fibroblast stimulation and fibrosis in aging and myocardial infarction. ECM1 may be a novel intermediary between inflammation and fibrosis. | 30789914 |
| 2018-10-06 12:17:00 | data identify ECM1 as a soluble protein to promote TFH cell differentiation and antibody production. | 30087185 |
| 2017-08-26 11:35:00 | ECM1 seems to be critical for PTHrP action in chondrogenesis, as blockage of ECM1 nearly abolishes PTHrP regulation of chondrocyte hypertrophy, and overexpression of ECM1 rescues disorganized growth plates of PTHrP-null mice; ECM1 and progranulin chondrogenic growth factor constitute an interaction network. | 27075243 |
| Type | IDs |
|---|---|
| Synonymous | AI663821, p85 |
| Gene |
UniProtKB-ID:
ECM1_MOUSE,
F8WI14_MOUSE
UniprotKB:
Q61508,
F8WI14
UniParc:
UPI00004351C0,
UPI000164C474,
UPI0000022DC5
EMBL:
AK153471,
AC093317,
AK153009,
L33416
Ensembl:
ENSMUSG00000028108
KO:
mmu:13601
|
| Nucleutide sequences |
EMBL-CDS:
BAE32022.1,
AAA37535.1,
BAE31648.1
Ensembl_TRS:
ENSMUST00000117507,
ENSMUST00000029753
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112665,
ENSMUSP00000029753
RefSeq:
NP_001341999.1,
NP_031925.2,
XP_011238311.1,
XP_017174939.1,
NP_001239582.1,
XP_030108273.1,
XP_011238310.1,
XP_017174938.1,
XP_006501047.1
|
| Others |
UniRef100:
UniRef100_Q61508,
UniRef100_F8WI14
UniRef90:
UniRef90_Q61508
UniRef50:
UniRef50_Q16610
UniGene:
Mm.3433
CCDS:
CCDS17619.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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